Evidence map›Paper›PMID 18377131›Full record

SynthesisHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2008

Stress management interventions for HIV+ adults: a meta-analysis of randomized controlled trials, 1989 to 2006.

Lori A J Scott-Sheldon, Seth C Kalichman, Michael P Carey, Robyn L Fielder

Open access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 11 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 11 syntheses or guidelines pooled it, 209 citations in OpenAlex.

  1. Stress management interventions for adults with heart failure: Systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021
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  5. Mindfulness-Based Interventions for Adults with Cardiovascular Disease: A Systematic Review and Meta-Analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2020
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  11. Review and meta-analysis of couple-oriented interventions for chronic illness.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2010
    Pooled it
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  19. Living with HIV: responses to a mantram intervention using the critical incident research method.Journal of alternative and complementary medicine (New York, N.Y.) · 2012
    Trial
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lori A J Scott-SheldonCenter for Health and Behavior, Syracuse University, Syracuse, NY 13244-2340, USA. lajss@syr.edu
Seth C Kalichman
Michael P Carey
Robyn L Fielder
Syracuse University · USUniversity of Connecticut · US

Funding

HIV PREVENTION FOR STD CLINIC PATIENTSR01MH068171 · NIMH · SYRACUSE UNIVERSITY · PI CAREY, MICHAEL P · 2003 to 2013
$5.6M
HIV Treatment Adherence/Risk Reduction IntegratedR01MH071164 · NIMH · UNIVERSITY OF CONNECTICUT STORRS · PI KALICHMAN, SETH C · 2005 to 2009
$3.0M
NIMH NIH HHS R01 MH068171NIMH NIH HHS R01-MH068171NIMH NIH HHS R01 MH071164NIMH NIH HHS R01-MH71164
6 · The paper itself

Abstract

objectiveNumerous studies document that stress accelerates disease processes in a variety of diseases including HIV. As a result, investigators have developed and evaluated interventions to reduce stress as a means to improve health among persons living with HIV. Therefore, the current meta-analysis examines the impact of stress-management interventions at improving psychological, immunological, hormonal, and other behavioral health outcomes among HIV+ adults.

designThis meta-analytic review integrated the results of 35 randomized controlled trials examining the efficacy of 46 separate stress management interventions for HIV+ adults (N=3,077).

main outcome measuresEffect sizes were calculated for stress processes (coping and social support), psychological/psychosocial (anxiety, depression, distress, and quality of life), immunological (CD4+ counts and viral load), hormonal (cortisol, dehydroepiandrosterone sulfate [DHEA-S], cortisol/DHEA-S ratio, and testosterone) and other behavioral health outcomes (fatigue).

resultsCompared to controls, stress-management interventions reduce anxiety, depression, distress, and fatigue and improve quality of life (d+s=0.16 to 0.38). Stress-management interventions do not appear to improve CD4+ counts, viral load, or hormonal outcomes compared with controls.

conclusionOverall, stress-management interventions for HIV+ adults significantly improve mental health and quality of life but do not alter immunological or hormonal processes. The absence of immunological or hormonal benefits may reflect the studies' limited assessment period (measured typically within 1-week postintervention), participants' advanced stage of HIV (HIV+ status known for an average of 5 years), and/or sample characteristics (predominately male and White participants). Future research might test these hypotheses and refine our understanding of stress processes and their amelioration.

Indexed as

Adaptation, PsychologicalArousalBehavior TherapyCD4 Lymphocyte CountDehydroepiandrosterone SulfateHIV SeropositivityHydrocortisonePyridinesRandomized Controlled Trials as TopicStress, PsychologicalTestosteroneViral LoadDehydroepiandrosterone SulfateHydrocortisonePyridinesTestosteroneV 10367

Identifiers

PMID18377131
PMCPMC2409585
OpenAlexW2024424432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.