ArticleThe New England journal of medicine2008
Does ENHANCE diminish confidence in lowering LDL or in ezetimibe?
Article in The New England journal of medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Simvastatin with or without ezetimibe in familial hypercholesterolemia (the ENHANCE trial).Current atherosclerosis reports · 2009Trial
- The Effect of Age and Comorbidities on the Association Between the Medicare STAR Oral Antihyperglycemic Adherence Metric and Glycemic Control.Journal of managed care & specialty pharmacy · 2018Observational
- Beyond Statins: Emerging Evidence for HDL-Increasing Therapies and Diet in Treating Cardiovascular Disease.Advances in preventive medicine · 2018Review
- Review
- Cholesterol treatment patterns and cardiovascular clinical outcomes associated with colesevelam HCl and ezetimibe.Drugs & aging · 2014Article
- Trends in use of ezetimibe after the ENHANCE trial, 2007 through 2010.JAMA internal medicine · 2014Article
- Ezetimibe therapy: mechanism of action and clinical update.Vascular health and risk management · 2012Review
- Therapies targeting exogenous cholesterol uptake: new insights and controversies.Current atherosclerosis reports · 2011Review
- Combination therapy of statin and ezetimibe for the treatment of familial hypercholesterolemia.Vascular health and risk management · 2010Review
- Article
- Review
- MR plaque imaging of the carotid artery.Neuroradiology · 2010Review
- Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia.Lipids in health and disease · 2009Article
- Cardiovascular magnetic resonance parameters of atherosclerotic plaque burden improve discrimination of prior major adverse cardiovascular events.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2009Article
- Simvastatin with or without ezetimibe in familial hypercholesterolemia.Current atherosclerosis reports · 2009Article
- Update of recent reforms in Germany to enhance the quality and efficiency of prescribing of proton pump inhibitors and lipid-lowering drugs.PharmacoEconomics · 2009Article
- Dyslipidemia in youth with diabetes: to treat or not to treat?The Journal of pediatrics · 2008Review
- Late-breaking trials at the ACC scientific sessions: insights and controversy.Current cardiology reports · 2008Article
- Assessment of new technologies: surrogate endpoints versus outcomes, and the cost of health care.Journal of nuclear cardiology : official publication of the American Society of Nuclear CardiologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
18376002What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.