ArticleThe Plant cell2008
The highly similar Arabidopsis homologs of trithorax ATX1 and ATX2 encode proteins with divergent biochemical functions.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 98 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
98 citing papers in PubMed.
- Azole-Driven Cross-Resistance and Transporter Gene Expression inMicroorganisms · 2026Article
- Epigenetic regulation of floral transition: pathways and players.Plant cell reports · 2026Review
- Integrated expression analysis to elucidate the role of miR394 during flowering in Arabidopsis thaliana.Plant cell reports · 2025Article
- Single amino acid mutations in histone H3.3 illuminate the functional significance of H3K4 methylation in plants.Nature communications · 2025Article
- Functions and Mechanisms of Histone Modifications in Plants.Annual review of plant biology · 2025Review
- NERD-dependent mNature plants · 2025Article
- The roles of epigenetic regulators in plant regeneration: Exploring patterns amidst complex conditions.Plant physiology · 2024Review
- Identification of watermelon H3K4 and H3K27 genes and their expression profiles during watermelon fruit development.Molecular biology reports · 2023Article
- Genetic Architecture of Flowering Time Differs Between Populations With Contrasting Demographic and Selective Histories.Molecular biology and evolution · 2023Article
- Histone H3K4 methyltransferase DcATX1 promotes ethylene induced petal senescence in carnation.Plant physiology · 2023Article
- Apple SUMO E3 ligase MdSIZ1 regulates cuticular wax biosynthesis by SUMOylating transcription factor MdMYB30.Plant physiology · 2023Article
- A chromosome-length genome assembly and annotation of blackberry (Rubus argutus, cv. "Hillquist").G3 (Bethesda, Md.) · 2023Article
- Oligosaccharide production and signaling correlate with delayed flowering in an Arabidopsis genotype grown and selected in high [CO2].PloS one · 2023Article
- A Green Light to Switch on Genes: Revisiting Trithorax on Plants.Plants (Basel, Switzerland) · 2022Review
- Transcription-coupled and epigenome-encoded mechanisms direct H3K4 methylation.Nature communications · 2022Article
- Regulatory Networks of Flowering Genes inPlants (Basel, Switzerland) · 2022Article
- Genome-Wide Identification and Characterization of SET Domain Family Genes inInternational journal of molecular sciences · 2022Article
- Article
- Epigenome and Epitranscriptome: Potential Resources for Crop Improvement.International journal of molecular sciences · 2021Review
- SDG712, a Putative H3K9-Specific Methyltransferase Encoding Gene, Delays Flowering through Repressing the Expression of Florigen Genes in Rice.Rice (New York, N.Y.) · 2021Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
- Correction · 2015-12-14Error in Image ·
- Erratum issuedCorrection.2016
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene duplication followed by functional specialization is a potent force in the evolution of biological diversity. A comparative study of two highly conserved duplicated genes, ARABIDOPSIS TRITHORAX-LIKE PROTEIN1 (ATX1) and ATX2, revealed features of both partial redundancy and of functional divergence. Although structurally similar, their regulatory sequences have diverged, resulting in distinct temporal and spatial patterns of expression of the ATX1 and ATX2 genes. We found that ATX2 methylates only a limited fraction of nucleosomes and that ATX1 and ATX2 influence the expression of largely nonoverlapping gene sets. Even when coregulating shared targets, ATX1 and ATX2 may employ different mechanisms. Most remarkable is the divergence of their biochemical activities: both proteins methylate K4 of histone H3, but while ATX1 trimethylates it, ATX2 dimethylates it. ATX2 and ATX1 provide an example of separated K4 di from K4 trimethyltransferase activity.
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