Thioredoxin-interacting protein is killing my beta-cells!

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. N6-methyladenosine (miScience · 2026
   Article
2. Thioredoxin-Interacting Protein in Cancer and Diabetes.Antioxidants & redox signaling · 2022
   Review
3. Thioredoxin, thioredoxin interacting protein and transducer and activator of transcription 3 in gestational diabetes.Molecular biology reports · 2020
   Article
4. The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker?Cellular and molecular life sciences : CMLS · 2018
   Review
5. The Function of Thioredoxin-Binding Protein-2 (TBP-2) in Different Diseases.Oxidative medicine and cellular longevity · 2018
   Review
6. Thioredoxin plays a key role in retinal neuropathy prior to endothelial damage in diabetic mice.Oncotarget · 2017
   Article
7. TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook.Current drug targets · 2017
   Review
8. Minireview: Thioredoxin-interacting protein: regulation and function in the pancreatic β-cell.Molecular endocrinology (Baltimore, Md.) · 2014
   Review
9. Thioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins in cancer and diabetes mellitus.Journal of clinical biochemistry and nutrition · 2012
   Article
10. Oxidative stress and beta-cell dysfunction.Pflugers Archiv : European journal of physiology · 2010
    Review
11. Glutaredoxin-1 mediates NADPH-dependent stimulation of calcium-dependent insulin secretion.Molecular endocrinology (Baltimore, Md.) · 2009
    Article
12. New insight into the mechanisms underlying the function of the incretin hormone glucagon-like peptide-1 in pancreatic β-cells: the involvement of the Wnt signaling pathway effector β-catenin.Islets
    Review
13. Adaptive and maladaptive roles for ChREBP in the liver and pancreatic islets.The Journal of biological chemistry
    Review

Corrections and comments

• Comment on
  Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.2008

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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