ArticleThe international journal of cardiovascular imaging2008
Assessment of atherosclerotic carotid plaque volume with multidetector computed tomography angiography.
Article in The international journal of cardiovascular imaging, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Why Current Detection of Vascular Calcification Falls Short and How to Improve on It.TH open : companion journal to thrombosis and haemostasis · 2024Review
- Machine Learning Detects Symptomatic Plaques in Patients With Carotid Atherosclerosis on CT Angiography.Circulation. Cardiovascular imaging · 2024Article
- Article
- CT imaging features of carotid artery plaque vulnerability.Annals of translational medicine · 2020Review
- Plaque imaging volume analysis: technique and application.Cardiovascular diagnosis and therapy · 2020Review
- The association of innate and adaptive immunity, subclinical atherosclerosis, and cardiovascular disease in the Rotterdam Study: A prospective cohort study.PLoS medicine · 2020Article
- Carotid Intraplaque-Hemorrhage Volume and Its Association with Cerebrovascular Events.AJNR. American journal of neuroradiology · 2019Article
- VASIM: an automated tool for the quantification of carotid atherosclerosis by computed tomography angiography.The international journal of cardiovascular imaging · 2019Article
- Automatic detection of carotid arteries in computed tomography angiography: a proof of concept protocol.The international journal of cardiovascular imaging · 2016Article
- Longitudinal assessment of carotid atherosclerosis after Radiation Therapy using Computed Tomography: A case control Study.European radiology · 2016Observational
- Dual energy computed tomography quantification of carotid plaques calcification: comparison between monochromatic and polychromatic energies with pathology correlation.European radiology · 2015Article
- Production of IL-8, VEGF and Elastase by Circulating and Intraplaque Neutrophils in Patients with Carotid Atherosclerosis.PloS one · 2015Article
- Computed tomography angiography vs 3 T black-blood cardiovascular magnetic resonance for identification of symptomatic carotid plaques.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2014Article
- Analysis of carotid artery plaque and wall boundaries on CT images by using a semi-automatic method based on level set model.Neuroradiology · 2012Article
- Carotid artery plaque classification: does contrast enhancement play a significant role?AJNR. American journal of neuroradiology · 2012Article
- Carotid atherosclerotic plaque progression and change in plaque composition over time: a 5-year follow-up study using serial CT angiography.AJNR. American journal of neuroradiology · 2012Article
- Automated versus manual segmentation of atherosclerotic carotid plaque volume and components in CTA: associations with cardiovascular risk factors.The international journal of cardiovascular imaging · 2012Article
- Distribution, size, and shape of abdominal aortic calcified deposits and their relationship to mortality in postmenopausal women.International journal of biomedical imaging · 2012Article
- Carotid artery wall thickness and leukoaraiosis: preliminary results using multidetector row CT angiography.AJNR. American journal of neuroradiology · 2011Article
- Potential of integrated [18F] fluorodeoxyglucose positron-emission tomography/CT in identifying vulnerable carotid plaques.AJNR. American journal of neuroradiology · 2011Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe amount of atherosclerotic plaque and its components (calcifications, fibrous tissue, and lipid core) could be better predictors of acute events than the now currently used degree of stenosis. Therefore, we evaluated a dedicated software tool for volume measurements of atherosclerotic carotid plaque and its components in multidetector computed tomography angiography (MDCTA) images. MATERIALS AND
methodsData acquisition was approved by the Institutional Review Board and all patients gave written informed consent. MDCTA images of 56 carotid arteries were analyzed by three observers. Plaque volumes were assessed by manual drawing of the outer vessel contour. The luminal boundary was determined based on a Hounsfield-Unit (HU) threshold. The contribution of different components was measured by the number of voxels within defined ranges of HU-values (calcification >130 HU, fibrous tissue 60-130 HU, lipid core <60 HU). Interobserver variability (IOV) was assessed.
resultsPlaque volume was 1,259 +/- 621 mm3. The calcified, fibrous and lipid volumes were 238 +/- 252 mm3, 647 +/- 277 mm3 and 376 +/- 283 mm3, respectively. IOV was moderate with interclass correlation coefficients (ICC) ranging from 0.76 to 0.99 and coefficients of variation (COV) ranging from 3% to 47%.
conclusionAtherosclerotic carotid plaque volume and plaque component volumes can be assessed with MDCTA with a reasonable observer variability.
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