Evidence map›Paper›PMID 18371592›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Arterial wall uptake of fluorodeoxyglucose on PET imaging in stable cancer disease patients indicates higher risk for cardiovascular events.

Benoît Paulmier, Michèle Duet, Raphaël Khayat, Nadia Pierquet-Ghazzar, Jean-Pierre Laissy, Christophe Maunoury, Florent Hugonnet, Elisabeth Sauvaget, Ludovic Trinquart, Marc Faraggi

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 167 citations in OpenAlex.

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  9. From incidental positron emission uptake toFrontiers in cardiovascular medicine · 2026
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  18. The application of molecular imaging to advance translational research in chronic inflammation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
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  19. Sleep duration and vascular inflammation using hybrid positron emission tomography/magnetic resonance imaging: results from the Multi-Ethnic Study of Atherosclerosis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Benoît PaulmierDepartment of Nuclear Medicine, Hôpital Européen Georges Pompidou (Assistance Publique-Hôpitaux de Paris), Paris, France. benoit.paulmier@egp.aphp.fr
Michèle Duet
Raphaël Khayat
Nadia Pierquet-Ghazzar
Jean-Pierre Laissy
Christophe Maunoury
Florent Hugonnet
Elisabeth Sauvaget
Ludovic Trinquart
Marc Faraggi
Assistance Publique – Hôpitaux de Paris · FRHôpital Européen Georges-Pompidou · FRUniversité Paris 8 · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to evaluate the additional information of 18 fluorodeoxyglucose (FDG) arterial uptake with respect to other conventional cardiovascular risk factors and arterial calcifications in patients with stable cancer. METHODS AND

resultsWe compared the rate of cardiovascular events in 2 groups of patients with (n = 45) and without (n = 56) enhanced arterial 18FDG uptake, matched for the main clinical parameters. The extent and intensity of 18FDG uptake were quantified. A calcification index was also determined. About one third of the selected patients had a history of cardiovascular events and thus could be defined as "vulnerable patients." Old cardiovascular events (>6 months before or after positron emission tomography [PET]) and recent cardiovascular events (<6 months before or after PET) were significantly more frequent in the high-FDG uptake group than in the low-FDG uptake group (48% vs 15%, respectively [P = .0006], and 30% vs 1.8%, respectively [P = .0002]). The extent of 18FDG arterial uptake was the unique factor significantly related to the occurrence of a recent event by either logistic regression or discriminant analysis (P = .004 for all). Conversely, calcium index was the single factor related to old events (P = .004 and P = .002, respectively).

conclusionsExtensive arterial 18FDG uptake might be an indicator of an evolving atherosclerotic process and should be mentioned in PET/computed tomography reports.

Indexed as

ArteriesAtherosclerosisFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedNeoplasmsPositron-Emission TomographyRadiopharmaceuticalsRisk AssessmentRisk FactorsFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID18371592
OpenAlexW1985787115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.