ReviewNeuroscience bulletin2008
Alzheimer's disease: epidemiology, genetics, and beyond.
Review in Neuroscience bulletin, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 65 citations in OpenAlex.
- Acupuncture for patients with mild to moderate Alzheimer's disease: a randomized controlled trial.BMC complementary and alternative medicine · 2017Trial
- Recent advances towards BACE1 drug discovery and therapeutics design.RSC medicinal chemistry · 2026Review
- Alzheimer's disease and its related dementias in US Native Americans: A major public health concern.Ageing research reviews · 2023Review
- Plasma β-amyloid, tau, neurodegeneration biomarkers and inflammatory factors of probable Alzheimer's disease dementia in Chinese individuals.Frontiers in aging neuroscience · 2022Article
- The Role of Medical Acupuncture Therapy in Alzheimer's Disease.Medical acupuncture · 2021Article
- Role of Withaferin A and Its Derivatives in the Management of Alzheimer's Disease: Recent Trends and Future Perspectives.Molecules (Basel, Switzerland) · 2021Review
- The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix.Molecules (Basel, Switzerland) · 2020Article
- Effects of huperzine A on hippocampal inflammatory response and neurotrophic factors in aged rats after anesthesia.Acta cirurgica brasileira · 2020Article
- Synergistic Inhibition of Acetylcholinesterase by Alkaloids Derived from Stephaniae Tetrandrae Radix, Coptidis Rhizoma and Phellodendri Chinensis Cortex.Molecules (Basel, Switzerland) · 2019Article
- Increased BBB permeability contributes to EGCG-caused cognitive function improvement in natural aging rats: pharmacokinetic and distribution analyses.Acta pharmacologica Sinica · 2019Article
- Article
- Bamboo leaf extract improves spatial learning ability in a rat model with senile dementia.Journal of Zhejiang University. Science. B · 2015Article
- Neuroprotective effects of leptin in the context of obesity and metabolic disorders.Neurobiology of disease · 2014Review
- Influence of deep brain stimulation of the subthalamic nucleus on cognitive function in patients with Parkinson's disease.Neuroscience bulletin · 2014Review
- Long-term oral administration of hop flower extracts mitigates Alzheimer phenotypes in mice.PloS one · 2014Article
- Fewer referrals to Swedish emergency departments among nursing home patients with dementia, comprehensive cognitive decline and multicomorbidity.The journal of nutrition, health & aging · 2012Article
- Unraveling the early events of amyloid-β protein (Aβ) aggregation: techniques for the determination of Aβ aggregate size.International journal of molecular sciences · 2012Review
- Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration.BMC endocrine disorders · 2010Article
- Expression of the apoptosis-related proteins caspase-3 and NF-kappaB in the hippocampus of Tg2576 mice.Neuroscience bulletin · 2010Article
- Conceptual evolution in Alzheimer's disease: implications for understanding the clinical phenotype of progressive neurodegenerative disease.Journal of Alzheimer's disease : JAD · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is an increasing epidemic threatening public health. Both men and women are susceptible to the disease although women are at a slightly higher risk. The prevalence of AD rises exponentially in elderly people from 1% at age of 65 to approximately 40%-50% by the age of 95. While the cause of the disease has not been fully understood, genetics plays a role in the onset of the disease. Mutations in three genes (APP, PSEN1, and PSEN2) have been found to cause AD and APOE4 allele increases the risk of the disease. As human genomic research progresses, more genes have been identified and linked with AD. Genetic screening tests for persons at high risk of AD are currently available and may help them as well as their families better prepare for a later life with AD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.