Evidence map›Paper›PMID 18368054›Full record

ReviewNature reviews. Genetics2008

Transposable elements and the evolution of regulatory networks.

Cédric Feschotte

Abstract readReview
In one paragraph

Review in Nature reviews. Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 731 papers.

0numbers the graph read from it
0cells of the map it votes in
731citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

731 citing papers in PubMed.

  1. Review
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  20. The gene revisited: historical foundations and postgenomic complexity.Theory in biosciences = Theorie in den Biowissenschaften · 2026
    Review

671 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Cédric FeschotteDepartment of Biology, Life Science Building, BOX 19498, University of Texas, Arlington, Texas 76019, USA. cedric@uta.edu

Funding

Human DNA transposons: evolutionary history and genomic impactR01GM077582 · NIGMS · UNIVERSITY OF UTAH · PI FESCHOTTE, CEDRIC · 2007 to 2015
$1.4M
NIGMS NIH HHS R01 GM077582
6 · The paper itself

Abstract

The control and coordination of eukaryotic gene expression rely on transcriptional and post-transcriptional regulatory networks. Although progress has been made in mapping the components and deciphering the function of these networks, the mechanisms by which such intricate circuits originate and evolve remain poorly understood. Here I revisit and expand earlier models and propose that genomic repeats, and in particular transposable elements, have been a rich source of material for the assembly and tinkering of eukaryotic gene regulatory systems.

Indexed as

AnimalsChromosome MappingDNA Transposable ElementsEukaryotic CellsGene Expression RegulationGenomeHumansDNA Transposable Elements

Identifiers

PMID18368054
PMCPMC2596197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.