ArticleJournal of clinical microbiology2008
Dynamic transmission of numerous Anaplasma phagocytophilum genotypes among lambs in an infected sheep flock in an area of anaplasmosis endemicity.
Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Temporal patterns of gene expression in response to inoculation with a virulent Anaplasma phagocytophilum strain in sheep.Scientific reports · 2023Article
- The Use of the Antigenically Variable Major Surface Protein 2 in the Establishment of Superinfection during Natural Tick Transmission of Anaplasma marginale in Southern Ghana.Infection and immunity · 2023Article
- Comparative Whole Genome Analysis of anPathogens (Basel, Switzerland) · 2022Article
- Article
- ExperimentalFrontiers in veterinary science · 2020Article
- Prevalence and co-infection with tick-borneInternational journal for parasitology. Parasites and wildlife · 2019Article
- A lifelong study of a pack Rhodesian ridgeback dogs reveals subclinical and clinical tick-borne Anaplasma phagocytophilum infections with possible reinfection or persistence.Parasites & vectors · 2018Article
- Co-circulation of different A. phagocytophilum variants within cattle herds and possible reservoir role for cattle.Parasites & vectors · 2018Article
- Survey of Anaplasma phagocytophilum and Anaplasma sp. 'Omatjenne' infection in cattle in Africa with special reference to Ethiopia.Parasites & vectors · 2018Article
- Lambs immunized with an inactivated variant of Anaplasma phagocytophilum.Acta veterinaria Scandinavica · 2015Article
- Multilocus sequence analysis of Anaplasma phagocytophilum reveals three distinct lineages with different host ranges in clinically ill French cattle.Veterinary research · 2014Article
- Restriction of Francisella novicida genetic diversity during infection of the vector midgut.PLoS pathogens · 2014Article
- Temporal and spatial variation in Anaplasma phagocytophilum infection in Swedish moose (Alces alces).Epidemiology and infection · 2014Article
- Anaplasma phagocytophilum--a widespread multi-host pathogen with highly adaptive strategies.Frontiers in cellular and infection microbiology · 2013Review
- Prophylactic treatment with flumethrin, a pyrethroid (Bayticol(®), Bayer), against Anaplasma phagocytophilum infection in lambs.Acta veterinaria Scandinavica · 2012Article
- Prevalence of Anaplasma phagocytophilum infection and effect on lamb growth.Acta veterinaria Scandinavica · 2011Article
- PCR detection of Anaplasma phagocytophilum in goat flocks in an area endemic for tick-borne fever in Switzerland.Parasite (Paris, France) · 2011Article
- Coexistence of pathogens in host-seeking and feeding ticks within a single natural habitat in Central Germany.Applied and environmental microbiology · 2010Article
- Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells.Nature reviews. Microbiology · 2010Review
- Variant -and individual dependent nature of persistent Anaplasma phagocytophilum infection.Acta veterinaria Scandinavica · 2010Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
The transmission dynamics of Anaplasma phagocytophilum strains circulating within juvenile members of a sheep flock grazing on an Ixodes ricinus-infested pasture in southern Norway were monitored. PCR-based detection of the bacterial p44 fragments in the blood of 16 lambs sampled weekly for 16 weeks following their release into pasture revealed rickettsemia in all animals, with an increasing proportion of infected animals as the survey progressed. Comparison of partial msp4 sequences obtained from infected blood samples revealed 24 distinct genotypes, some of which were repeatedly encountered, occurring in up to six sheep over a 14-week period, whereas others were observed only once. Individual sheep were infected by up to five distinct genotypes, with a specific genotype being encountered for between one and three consecutive weeks, and in some sheep, genotypes detected early in the study were also present in later samples. In general, detection of A. phagocytophilum by PCR correlated well with the observation of infected neutrophils in blood smears. Together these results reveal a previously unrecognized diversity of A. phagocytophilum strains simultaneously circulating within an infected population in an area of endemicity and are consistent with a remarkably dynamic transmission of strains among infected animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.