ReviewCurrent atherosclerosis reports2008
Recognizing and improving patient nonadherence to statin therapy.
Review in Current atherosclerosis reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Meta-analyses of Theory Use in Medication Adherence Intervention Research.American journal of health behavior · 2016Pooled it
- Packaging interventions to increase medication adherence: systematic review and meta-analysis.Current medical research and opinion · 2015Pooled it
- Medication adherence interventions that target subjects with adherence problems: Systematic review and meta-analysis.Research in social & administrative pharmacy : RSAPPooled it
- A simple informative intervention in primary care increases statin adherence.European journal of clinical pharmacology · 2016 · on this mapTrial
- The RISAP-study: a complex intervention in risk communication and shared decision-making in general practice.BMC family practice · 2010Trial
- Perceptions and Knowledge of Cholesterol and Lipid-Lowering Medications Among Treatment-Naive Individuals: A Cross-Sectional Study.Patient preference and adherence · 2025Article
- American College of Physicians Ethical Guidance for Electronic Patient-Physician Communication: Aligning Expectations.Journal of general internal medicine · 2020Article
- Reasons for Nonadherence to Statins - A Systematic Review of Reviews.Patient preference and adherence · 2020Review
- Adherence to Treatment in Stroke Patients.International journal of environmental research and public health · 2019Article
- How Health Care Professionals Evaluate a Digital Intervention to Improve Medication Adherence: Qualitative Exploratory Study.JMIR human factors · 2018Article
- Gender differences in statin prescription rates, adequacy of dosing, and association of statin therapy with outcome after heart failure hospitalization: a retrospective analysis in a community setting.European journal of clinical pharmacology · 2016Article
- Article
- Understanding patients' perspective of statin therapy: can we design a better approach to the management of dyslipidaemia? A literature review.Singapore medical journal · 2014Review
- Risk awareness in secondary stroke prevention: a review of the literature.JRSM cardiovascular disease · 2014Article
- Risk of cardiovascular disease? A qualitative study of risk interpretation among patients with high cholesterol.BMC family practice · 2013Article
- Will cardiovascular disease prevention widen health inequalities?PLoS medicine · 2010Review
- Postpartum diabetes screening: adherence rate and the performance of fasting plasma glucose versus oral glucose tolerance test.Diabetes care · 2009Article
- Improving the physician-patient cardiovascular risk dialogue to improve statin adherence.BMC family practice · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite landmark trials demonstrating the benefits of statin therapy for lipid lowering and in the primary and secondary prevention of acute coronary events, many patients do not adhere to medication regimens. Although incremental gains have been made in lowering the absolute levels of total serum cholesterol in the general population, only one third of treated patients are achieving their lipid goals, with fewer than 20% of patients with cardiovascular disease at their target lipid goals. Only half of patients continue taking statins prescribed to them at 6 months, and only 30% to 40% continue taking them at 1 year. Predictors of poor adherence to statins are described, such as female gender and low socioeconomic status. Approaches that are physician focused and patient centered, such as frequent follow-up and serum lipid testing and better education of patients about cardiovascular disease, are suggested to offset a major impediment to achieving the full therapeutic outcomes promised by clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.