ArticleGenome biology2008
Analysis of repetitive DNA distribution patterns in the Tribolium castaneum genome.
Article in Genome biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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44 citing papers in PubMed, 64 citations in OpenAlex.
- Deeply conserved and expressed small ORFs in the model beetle Tribolium castaneum.BMC biology · 2026Article
- Species-rich and genomically diverse: comparative genomics reveals how fusions, fissions, and sex chromosomes have shaped beetle evolution.bioRxiv : the preprint server for biology · 2026Article
- A new piece in the repeatome puzzle of Triatominae bugs: The analysis of Triatoma rubrofasciata reveals the role of satellite DNAs in the karyotypic evolution of distinct lineages.Insect molecular biology · 2025Article
- Pytrf: a python package for finding tandem repeats from genomic sequences.BMC bioinformatics · 2025Article
- Long-read genome assembly of the insect model organismGenome research · 2024Article
- Satellitome Analysis ofInternational journal of molecular sciences · 2024Article
- Comprehensive analysis of the Xya riparia genome uncovers the dominance of DNA transposons, LTR/Gypsy elements, and their evolutionary dynamics.BMC genomics · 2024Article
- Annotation of transposable elements in the transcriptome of the Neotropical brown stink bug Euschistus heros and its chromosomal distribution.Molecular genetics and genomics : MGG · 2023Article
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- Reference-Guided De Novo Genome Assembly of the Flour BeetleInternational journal of molecular sciences · 2022Article
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- Genome size evolution in the beetle genus Diabrotica.G3 (Bethesda, Md.) · 2022Article
- Satellitome Analysis and Transposable Elements Comparison in Geographically Distant Populations ofLife (Basel, Switzerland) · 2022Article
- The Genome ofGenes · 2022Article
- Genome-wide oscillations in G + C density and sequence conservation.Genome research · 2021Article
- A highly-contiguous genome assembly of the Eurasian spruce bark beetle, Ips typographus, provides insight into a major forest pest.Communications biology · 2021Article
- Article
- Satellitome Analysis ofInternational journal of molecular sciences · 2021Article
- Distinct Regulation of the Expression of Satellite DNAs in the BeetleInternational journal of molecular sciences · 2020Article
- CenH3 distribution reveals extended centromeres in the model beetle Tribolium castaneum.PLoS genetics · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundInsect genomes vary widely in size, a large fraction of which is often devoted to repetitive DNA. Re-association kinetics indicate that up to 42% of the genome of the red flour beetle, Tribolium castaneum, is repetitive. Analysis of the abundance and distribution of repetitive DNA in the recently sequenced genome of T. castaneum is important for understanding the structure and function of its genome.
resultsUsing TRF, TEpipe and RepeatScout we found that approximately 30% of the T. castaneum assembled genome is composed of repetitive DNA. Of this, 17% is found in tandem arrays and the remaining 83% is dispersed, including transposable elements, which in themselves constitute 5-6% of the genome. RepeatScout identified 31 highly repetitive DNA elements with repeat units longer than 100 bp, which constitute 7% of the genome; 65% of these highly repetitive elements and 74% of transposable elements accumulate in regions representing 40% of the assembled genome that is anchored to chromosomes. These regions tend to occur near one end of each chromosome, similar to previously described blocks of pericentric heterochromatin. They contain fewer genes with longer introns, and often correspond with regions of low recombination in the genetic map.
conclusionOur study found that transposable elements and other repetitive DNA accumulate in certain regions in the assembled T. castaneum genome. Several lines of evidence suggest these regions are derived from the large blocks of pericentric heterochromatin in T. castaneum chromosomes.
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