ArticleBMC bioinformatics2008
MausDB: an open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects.
Article in BMC bioinformatics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing.Computational and structural biotechnology journal · 2025Article
- Knockout mouse models as a resource for the study of rare diseases.Mammalian genome : official journal of the International Mammalian Genome Society · 2023Article
- TopoDB: a novel multifunctional management system for laboratory animal colonies.Database : the journal of biological databases and curation · 2020Article
- RodentSQL: a software suite for colony management of animal protocols.Future science OA · 2018Article
- Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2016Article
- Principles and application of LIMS in mouse clinics.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Review
- A review of standardized metabolic phenotyping of animal models.Mammalian genome : official journal of the International Mammalian Genome Society · 2014Review
- LAS: a software platform to support oncological data management.Journal of medical systems · 2012Article
- Innovations in phenotyping of mouse models in the German Mouse Clinic.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Article
- Conditional Allele Mouse Planner (CAMP): software to facilitate the planning and design of breeding strategies involving mice with conditional alleles.Transgenic research · 2012Article
- Laboratory Animal Management Assistant (LAMA): a LIMS for active research colonies.Mammalian genome : official journal of the International Mammalian Genome Society · 2010Article
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Authors and funding
6 authors.
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Abstract
backgroundLarge-scale, comprehensive and standardized high-throughput mouse phenotyping has been established as a tool of functional genome research by the German Mouse Clinic and others. In all these projects, vast amounts of data are continuously generated and need to be stored, prepared for data-mining procedures and eventually be made publicly available. Thus, central storage and integrated management of mouse phenotype data, genotype data, metadata and linked external data are highly important. Requirements most probably depend on the individual mouse housing unit or project and the demand for either very specific individual database solutions or very flexible solutions that can be easily adapted to local demands. Not every group has the resources and/or the know-how to develop software for this purpose. A database application has been developed for the German Mouse Clinic in order to meet all requirements mentioned above.
resultsWe present MausDB, the German Mouse Clinic web-based database application that integrates standard mouse colony management, phenotyping workflow scheduling features and mouse phenotyping result data management. It links mouse phenotype data with genotype data, metadata and external data such as public web databases, which is a prerequisite for comprehensive data analysis and mining. We describe how this can be achieved with a lean and user-friendly system built on open standards.
conclusionMausDB is suited for large-scale, high-throughput phenotyping facilities but can also be used exclusively for mouse colony management within smaller units or projects. The system is successfully used as the primary mouse and data management tool of the German Mouse Clinic and other mouse facilities. We offer MausDB to the scientific community as open source software to provide a system for storage of data from functional genomics projects in a well-structured, easily accessible form.
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