Evidence map›Paper›PMID 18365207›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2008

Endoscopic biopsy during third ventriculostomy in paediatric pineal region tumours.

Yahia Z Al-Tamimi, Deepti Bhargava, Surash Surash, Roberto E Ramirez, Federica Novegno, Darach W Crimmins, Atul K Tyagi, Paul D Chumas

Abstract read
PubMed Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Biopsy of Pineal Tumors: Endoscopy or Stereotaxic or Neuronavigation Guided?Advances and technical standards in neurosurgery · 2026
    Pooled it
  2. Article
  3. Review
  4. Pineal/germ cell tumors and pineal parenchymal tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
  5. Neuroendoscopy in the management of pineal region tumours in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  6. Article
  7. Article
  8. Pineal region tumors: pathophysiological mechanisms of presenting symptoms.American journal of translational research · 2021
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Ventricular endoscopy in the pediatric population: review of indications.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014
    Review
  15. Review
  16. Iatrogenic diplopia [corrected].International ophthalmology · 2014
    Review
  17. Review
  18. Review
  19. Gliomas of the pineal region.Journal of neuro-oncology · 2013
    Article
  20. Surgical pathway and management of pineal region tumours in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yahia Z Al-TamimiNeurosurgery Department, Level G Jubilee Wing, Leeds General Infirmary, Great George Street, Leeds, West Yorkshire, LS1 3EX, UK. yahia27@hotmail.com
Deepti Bhargava
Surash Surash
Roberto E Ramirez
Federica Novegno
Darach W Crimmins
Atul K Tyagi
Paul D Chumas
Leeds General Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectsThe goal of the study was to establish if endoscopic biopsy during third ventriculostomy contributes to morbidity in the management of paediatric pineal region tumours presenting with hydrocephalus. MATERIALS AND

methodsThis study was a retrospective descriptive study in patients less than 18 years of age who have presented with a pineal region tumour between 2000 and 2006. Data were obtained from case notes. Twelve patients had presented with a pineal region mass with symptomatic hydrocephalus. Of these, eight had endoscopic biopsy during third ventriculostomy.

conclusionsNo mortality or permanent morbidity was seen following endoscopic biopsy. Two cases of transient worsening of pre-operative diplopia were noted. Diagnostic sensitivity for endoscopic biopsy is 75%. Tumour markers were not significantly raised in any plasma and cerebrospinal fluid samples. Endoscopic biopsy during third ventriculostomy in paediatric pineal region tumours is safe and results in good diagnostic yields. It should play an integral role in the initial management of patients in this setting.

Indexed as

AdolescentBiopsyBrain NeoplasmsChildHumansHydrocephalusNeuroendoscopyPineal GlandPinealomaRetrospective StudiesThird VentricleVentriculostomy

Identifiers

PMID18365207
OpenAlexW1999713326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.