Evidence map›Paper›PMID 18365031›Full record

SynthesisPLoS neglected tropical diseases2008

Controlling soil-transmitted helminthiasis in pre-school-age children through preventive chemotherapy.

Marco Albonico, Henrietta Allen, Lester Chitsulo, Dirk Engels, Albis-Francesco Gabrielli, Lorenzo Savioli

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 9 pooled it
8.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 9 syntheses or guidelines pooled it, 256 citations in OpenAlex.

  1. Pooled it
  2. Meta-analysis and public policy: Reconciling the evidence on deworming.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Pooled it
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  4. Zoonotic Ancylostomiasis: An Update of a Continually Neglected Zoonosis.The American journal of tropical medicine and hygiene · 2020
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62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Marco AlbonicoIvo de Carneri Foundation (IdCF), Milano, Italy. albonico@tin.it
Henrietta Allen
Lester Chitsulo
Dirk Engels
Albis-Francesco Gabrielli
Lorenzo Savioli
World Health Organization · CHIngegneria dei Sistemi (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pre-school age children account for 10%-20% of the 2 billion people worldwide who are infected with soil-transmitted helminths (STHs): Ascaris lumbricoides (roundworm), Trichuris trichiura (whipworm), and Ancylostoma duodenale/Necator americanus (hookworms). Through a systematic review of the published literature and using information collated at World Health Organization headquarters, this paper summarizes the available evidence to support the recommendation that pre-school children should be included in regular deworming programmes. The first section describes the burden of STH disease in this age group, followed by a summary of how infection impacts iron status, growth, vitamin A status, and cognitive development and how STHs may exacerbate other high mortality infections. The second section explores the safety of the drugs themselves, given alone or co-administered, drug efficacy, and the importance of safe administration. The third section provides country-based evidence to demonstrate improved health outcomes after STH treatment. The final section provides country experiences in scaling up coverage of pre-school children by using other large scale public health interventions, including vitamin A programmes, immunization campaigns, and Child Health days. The paper concludes with a number of open research questions and a summary of some of the operational challenges that still need to be addressed.

Indexed as

AncylostomaAnimalsAnthelminticsAscaris lumbricoidesChildChild, PreschoolFemaleHelminthiasisHumansInfantMaleNecator americanusPreventive MedicineSoilTrichurisAnthelminticsSoil

Identifiers

PMID18365031
PMCPMC2274864
OpenAlexW1991082344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.