Evidence map›Paper›PMID 18364728›Full record

ReviewNature reviews. Microbiology2008

Searching for the cause of Kawasaki disease--cytoplasmic inclusion bodies provide new insight.

Anne H Rowley, Susan C Baker, Jan M Orenstein, Stanford T Shulman

Open access · bronzeAbstract readReview
In one paragraph

Review in Nature reviews. Microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 3 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 3 syntheses or guidelines pooled it, 156 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
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  9. Review
  10. Gut Microbiota Alterations in Patients With Kawasaki Disease.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  11. Article
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  16. Review
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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Anne H RowleyDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, The Center for Kawasaki Disease, The Children's Memorial Hospital, Chicago, Illinois 60611, USA. rowley@northwestern.edu
Susan C Baker
Jan M Orenstein
Stanford T Shulman
Northwestern University · USGeorge Washington University · USLoyola University Chicago · US

Funding

The Pathogenesis of Kawasaki DiseaseR01HL063771 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ROWLEY, ANNE H · 2000 to 2011
$3.6M
NHLBI NIH HHS HL63771NHLBI NIH HHS R01 HL063771
6 · The paper itself

Abstract

Kawasaki disease (KD) has emerged as the most common cause of acquired heart disease in children in the developed world. The cause of KD remains unknown, although an as-yet unidentified infectious agent might be responsible. By determining the causative agent, we can improve diagnosis, therapy and prevention of KD. Recently, identification of an antigen-driven IgA response that was directed at cytoplasmic inclusion bodies in KD tissues has provided new insights that could unlock the mysteries of KD.

Indexed as

AdultAntigensChildCoronary AneurysmCytoplasmHumansImmunoglobulin AInclusion BodiesMucocutaneous Lymph Node SyndromePlasma CellsAntigensImmunoglobulin A

Identifiers

PMID18364728
PMCPMC7097362
OpenAlexW2071719184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.