ArticleAnalytical chemistry2008
Sizing subcellular organelles and nanoparticles confined within aqueous droplets.
Article in Analytical chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- On-demand droplet formation at a T-junction: modelling and validation.Microsystems & nanoengineering · 2025Article
- Attomole-Level Multiplexed Detection of Neurochemicals in Picoliter Droplets by On-Chip Nanoelectrospray Ionization Coupled to Mass Spectrometry.Analytical chemistry · 2022Article
- DisPhaseDB: An integrative database of diseases related variations in liquid-liquid phase separation proteins.Computational and structural biotechnology journal · 2022Article
- Micro- and Nano-Devices for Studying Subcellular Biology.Small (Weinheim an der Bergstrasse, Germany) · 2021Review
- Tracking Bulk and Interfacial Diffusion Using Multiplex Coherent Anti-Stokes Raman Scattering Correlation Spectroscopy.The journal of physical chemistry. B · 2016Article
- One in a million: flow cytometric sorting of single cell-lysate assays in monodisperse picolitre double emulsion droplets for directed evolution.Analytical chemistry · 2014Article
- Analytical tools for characterizing heterogeneity in organelle content.Current opinion in chemical biology · 2012Review
- Investigating lyophilization of lipid nanocapsules with fluorescence correlation spectroscopy.Langmuir : the ACS journal of surfaces and colloids · 2010Article
- Droplets for ultrasmall-volume analysis.Analytical chemistry · 2009Article
- Chemistry and biology in femtoliter and picoliter volume droplets.Accounts of chemical research · 2009Article
- Sampling and electrophoretic analysis of segmented flow streams using virtual walls in a microfluidic device.Analytical chemistry · 2008Article
- Micro and Nano-Scale Technologies for Cell Mechanics.NanobiomedicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This article describes two complementary techniques, single-particle tracking and correlation spectroscopy, for accurately sizing nanoparticles confined within picoliter volume aqueous droplets. Single-particle tracking works well with bright particles that can be continuously illuminated and imaged, and we demonstrated this approach for sizing single fluorescent beads. Fluorescence correlation spectroscopy detects small intensity bursts from particles or molecules diffusing through the confocal probe volume, which works well with dim and rapidly diffusing particles or molecules; we demonstrated FCS for sizing synaptic vesicles confined in aqueous droplets. In combination with recent advances in droplet manipulations and analysis, we anticipate this capability to size single nanoparticles and molecules in free solution will complement existing tools for probing cellular systems, subcellular organelles, and nanoparticles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.