ReviewBritish journal of pharmacology2008
Genetic factors influencing alcohol dependence.
Review in British journal of pharmacology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 187 citations in OpenAlex.
- Early life stress paired with adolescent alcohol consumption reduces two-bottle choice alcohol consumption in mice.Alcohol, clinical & experimental research · 2025Article
- Retrieval of an Ethanol-Conditioned Taste Aversion Promotes GABAergic Plasticity in the Anterior Insular Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Effects of early life stress paired with adolescent alcohol consumption on two-bottle choice alcohol drinking behaviors in mice.bioRxiv : the preprint server for biology · 2024Article
- Retrieval of an ethanol-conditioned taste aversion promotes GABAergic plasticity in the insular cortex.bioRxiv : the preprint server for biology · 2024Article
- Bridging the Gap: A Holistic View of Personality Factors in Individuals With and Without Alcohol Use.Cureus · 2024Review
- 5. Collaborative Study on the Genetics of Alcoholism: Functional genomics.Genes, brain, and behavior · 2023Review
- Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.Cell genomics · 2023Article
- The Ratio of Second and Fourth Digit Length: A Biomarker for Methamphetamine Dependence?Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2022Article
- Alcohol Use Disorder: Neurobiology and Therapeutics.Biomedicines · 2022Review
- Gut microbiota and voluntary alcohol consumption.Translational psychiatry · 2022Article
- Non-coding RNA in alcohol use disorder by affecting synaptic plasticity.Experimental brain research · 2022Review
- Polygenic risk prediction based on singular value decomposition with applications to alcohol use disorder.BMC bioinformatics · 2022Article
- Influence of dopamine-related genes on craving, impulsivity, and aggressiveness in Korean males with alcohol use disorder.European archives of psychiatry and clinical neuroscience · 2021Article
- Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders.Molecular psychiatry · 2021Article
- Differential effects of early exposure to alcohol on alcohol preference and blood alcohol levels in low- and high-anxious rats.Experimental brain research · 2020Article
- Flying Together:International journal of molecular sciences · 2020Review
- Pharmacotherapeutic management of co-morbid alcohol and opioid use.Expert opinion on pharmacotherapy · 2020Review
- A Single Nucleotide Polymorphism Within Molybdenum Cofactor Sulfurase Gene Is Associated With Neuropsychiatric Conditions.Frontiers in molecular biosciences · 2020Article
- Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism.Translational psychiatry · 2019Article
- Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook.Alcohol (Fayetteville, N.Y.) · 2019Review
29 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Plentiful data from both animal and human studies support the importance of genetic influences in substance abuse and dependence (Bierut et al., 1998; Tsuang et al., 1998; Kendler et al., 2003). This review summarizes the evidence supporting such genetic influences, places them into perspective regarding animal and human studies, discusses the importance of both genes and environment, and highlights some specific genes of interest regarding the vulnerabilities for problems associated with alcohol use disorders. A long history of repetitive heavy use of alcohol exists across generations as well as the high prevalence of alcohol-related problems in Western societies. Moreover, the information offered here addresses the importance of more general issues regarding genetics and gene expression related to alcohol abuse and dependence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.