Evidence map›Paper›PMID 18362186›Full record

ArticleAntimicrobial agents and chemotherapy2008

Plasma and cerebrospinal fluid pharmacokinetics of moxifloxacin in a patient with tuberculous meningitis.

J W C Alffenaar, P M de Vries, G J Luijckx, D van Soolingen, T S van der Werf, R van Altena

Registry-linked trialAbstract readCase ReportsLetter
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02409290 (STREAM), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02409290 phase3completednot on this mapstarted 2016, after this paper: background citation

STREAM: The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB

TypeinterventionalSponsorIUATLD, IncRan2016 to 2023Enrolled588ConditionsMDR-TBArmsRegimen A locally-used WHO-approved MDR-TB regimen (2011 guideline), Moxifloxacin, Clofazimine, Ethambutol, Pyrazinamide
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

J W C Alffenaar
P M de Vries
G J Luijckx
D van Soolingen
T S van der Werf
R van Altena
University Medical Center Groningen · NLUniversity of Groningen · NLNational Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsAdultArea Under CurveAza CompoundsDrug MonitoringFluoroquinolonesHumansMaleMoxifloxacinQuinolinesTuberculosis, MeningealAnti-Bacterial AgentsAza CompoundsFluoroquinolonesMoxifloxacinQuinolines

Identifiers

PMID18362186
PMCPMC2415813
OpenAlexW2165809507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.