Evidence map›Paper›PMID 18361491›Full record

ArticleJournal of the American Chemical Society2008

Quantum dot nanobarcodes: epitaxial assembly of nanoparticle-polymer complexes in homogeneous solution.

Jian Yang, Shivang R Dave, Xiaohu Gao

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Rare-earth upconverting nanobarcodes for multiplexed biological detection.Small (Weinheim an der Bergstrasse, Germany) · 2011
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jian YangDepartment of Bioengineering, University of Washington, William H. Foege Building N530M, Campus Box 355061, Seattle, Washington 98195, USA.
Shivang R Dave
Xiaohu Gao

Funding

Sensitive and multiplexed analysis of cancer biomarkers with QD barcodesR01CA131797 · NCI · UNIVERSITY OF WASHINGTON · PI GAO, XIAOHU · 2008 to 2012
$1.6M
NCI NIH HHS R01 CA131797
6 · The paper itself

Abstract

Multiplexed nanobarcodes have been prepared with quantum dots (QDs) and alternating amphiphilic copolymers consisting of hydrocarbons and maleic anhydride groups. In homogeneous solution, the QD-polymer complexes grow epitaxially into nanobeads of narrow size dispersity, which has been previously achieved only for micrometer-sized beads in the presence of solid supports. As a result of this new nanostructure formation mechanism, more than 250 QDs can be loaded into a nanobead of 100 nm in diameter. A model assay for sensitive detection of human prostate specific antigen has also been demonstrated using the QD-nanobeads as fluorescent reporters. This nanoparticle-polymer self-assembly technology is capable of producing a variety of nanostructures and is expected to open new opportunities in nanoparticle-based ultrasensitive detection and imaging.

Indexed as

Quantum DotsColorHumansImmunoassayMicroscopy, Electron, TransmissionPolymersProstate-Specific AntigenSolutionsPolymersProstate-Specific AntigenSolutions

Identifiers

PMID18361491
PMCPMC2632979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.