ArticleApplied and environmental microbiology2008
Comparative genomics of "Dehalococcoides ethenogenes" 195 and an enrichment culture containing unsequenced "Dehalococcoides" strains.
Article in Applied and environmental microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Meta-analyses of Dehalococcoides mccartyi strain 195 transcriptomic profiles identify a respiration rate-related gene expression transition point and interoperon recruitment of a key oxidoreductase subunit.Applied and environmental microbiology · 2014Pooled it
- Differentiating Closely AffiliatedApplied and environmental microbiology · 2022Article
- Structural dynamics and transcriptomic analysis of Dehalococcoides mccartyi within a TCE-Dechlorinating community in a completely mixed flow reactor.Water research · 2019Article
- Metagenomic and Metatranscriptomic Analyses Reveal the Structure and Dynamics of a Dechlorinating Community Containing Dehalococcoides mccartyi and Corrinoid-Providing Microorganisms under Cobalamin-Limited Conditions.Applied and environmental microbiology · 2017Article
- Sustainable growth of Dehalococcoides mccartyi 195 by corrinoid salvaging and remodeling in defined lactate-fermenting consortia.Applied and environmental microbiology · 2014Article
- Article
- Characterization of four TCE-dechlorinating microbial enrichments grown with different cobalamin stress and methanogenic conditions.Applied microbiology and biotechnology · 2013Article
- The restricted metabolism of the obligate organohalide respiring bacterium Dehalobacter restrictus: lessons from tiered functional genomics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Article
- Overview of organohalide-respiring bacteria and a proposal for a classification system for reductive dehalogenases.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2013Review
- Diversity of reductive dehalogenase genes from environmental samples and enrichment cultures identified with degenerate primer PCR screens.Frontiers in microbiology · 2013Article
- Metagenomic analysis of a stable trichloroethene-degrading microbial community.The ISME journal · 2012Article
- Molecular techniques in the biotechnological fight against halogenated compounds in anoxic environments.Microbial biotechnology · 2012Review
- Global transcriptomic and proteomic responses of Dehalococcoides ethenogenes strain 195 to fixed nitrogen limitation.Applied and environmental microbiology · 2012Article
- Transcriptional analysis of a Dehalococcoides-containing microbial consortium reveals prophage activation.Applied and environmental microbiology · 2012Article
- Sustainable syntrophic growth of Dehalococcoides ethenogenes strain 195 with Desulfovibrio vulgaris Hildenborough and Methanobacterium congolense: global transcriptomic and proteomic analyses.The ISME journal · 2012Article
- Ecogenomics of microbial communities in bioremediation of chlorinated contaminated sites.Frontiers in microbiology · 2012Article
- Design and verification of a pangenome microarray oligonucleotide probe set for Dehalococcoides spp.Applied and environmental microbiology · 2011Article
- Role of "Dehalococcoides" spp. in the anaerobic transformation of hexachlorobenzene in European rivers.Applied and environmental microbiology · 2011Article
- Site-specific mobilization of vinyl chloride respiration islands by a mechanism common in Dehalococcoides.BMC genomics · 2011Article
- Comparative genomics of two newly isolated Dehalococcoides strains and an enrichment using a genus microarray.The ISME journal · 2011Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Tetrachloroethene (PCE) and trichloroethene (TCE) are prevalent groundwater contaminants that can be completely reductively dehalogenated by some "Dehalococcoides" organisms. A Dehalococcoides-organism-containing microbial consortium (referred to as ANAS) with the ability to degrade TCE to ethene, an innocuous end product, was previously enriched from contaminated soil. A whole-genome photolithographic microarray was developed based on the genome of "Dehalococcoides ethenogenes" 195. This microarray contains probes designed to hybridize to >99% of the predicted protein-coding sequences in the strain 195 genome. DNA from ANAS was hybridized to the microarray to characterize the genomic content of the ANAS enrichment. The microarray results revealed that the genes associated with central metabolism, including an apparently incomplete carbon fixation pathway, cobalamin-salvaging system, nitrogen fixation pathway, and five hydrogenase complexes, are present in both strain 195 and ANAS. Although the gene encoding the TCE reductase, tceA, was detected, 13 of the 19 reductive dehalogenase genes present in strain 195 were not detected in ANAS. Additionally, 88% of the genes in predicted integrated genetic elements in strain 195 were not detected in ANAS, consistent with these elements being genetically mobile. Sections of the tryptophan operon and an operon encoding an ABC transporter in strain 195 were also not detected in ANAS. These insights into the diversity of Dehalococcoides genomes will improve our understanding of the physiology and evolution of these bacteria, which is essential in developing effective strategies for the bioremediation of PCE and TCE in the environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.