ReviewThe Journal of physiology2008
Dynamic ATP signalling and neural development.
Review in The Journal of physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 77 citations in OpenAlex.
- Kolliker's Organ and Its Functional Role in the Development of Corti's Organ and Auditory Systems.Audiology research · 2025Review
- Activation of AMPK/OPA1 pathway alleviates traumatic brain damage by regulating mitophagy.Acta cirurgica brasileira · 2025Article
- Mechanisms of Diseases Associated with Mutation in GJC2/Connexin 47.Biomolecules · 2023Review
- P2X7 receptor activation awakes a dormant stem cell niche in the adult spinal cord.Frontiers in cellular neuroscience · 2023Article
- Enzyme histochemistry: a useful tool for examining the spatial distribution of brain ectonucleotidases in (patho)physiological conditions.Histology and histopathology · 2022Review
- Review
- COInternational journal of molecular sciences · 2021Review
- Purinergic signaling in the retina: From development to disease.Brain research bulletin · 2019Review
- Purinergic Signaling and Cochlear Injury-Targeting the Immune System?International journal of molecular sciences · 2019Review
- Role of Ectonucleotidases in Synapse Formation During Brain Development: Physiological and Pathological Implications.Current neuropharmacology · 2019Review
- Adenosine AAnatomical record (Hoboken, N.J. : 2007) · 2018Article
- Purinergic signalling during development and ageing.Purinergic signalling · 2015Review
- Connexins and gap junctions in the inner ear--it's not just about K⁺ recycling.Cell and tissue research · 2015Review
- ATP acting through P2Y receptors causes activation of podocyte TRPC6 channels: role of podocin and reactive oxygen species.American journal of physiology. Renal physiology · 2014Article
- Kölliker's organ and the development of spontaneous activity in the auditory system: implications for hearing dysfunction.BioMed research international · 2014Review
- Atrial fibrillation-linked germline GJA5/connexin40 mutants showed an increased hemichannel function.PloS one · 2014Article
- PKC-dependent ERK phosphorylation is essential for P2X7 receptor-mediated neuronal differentiation of neural progenitor cells.Cell death & disease · 2013Article
- Implications of purinergic receptor-mediated intracellular calcium transients in neural differentiation.Cell communication and signaling : CCS · 2013Article
- Hypothalamic tanycytes: potential roles in the control of feeding and energy balance.Trends in neurosciences · 2013Review
- Paracrine signaling through plasma membrane hemichannels.Biochimica et biophysica acta · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purinergic signalling plays a major role in the function of every organ including the brain. A growing body of evidence also suggests that purinergic signalling is important in the development of the retina, cochlea and neocortex. In these three contexts release of ATP through the spontaneous gating of connexin hemichannels in cells, respectively, of the retinal pigment epithelium, Köllicker's organ, and the radial glia triggers waves of intracellular Ca(2+) release. In the case of the developing retina and cortex, the released ATP acts to control proliferation of neuronal precursor cells, while in the cochlea it coordinates the spontaneous activity of adjacent hair cells to refine the tonotopic maps in the cochlear nucleus. Recently ATP-derived ADP signalling has been implicated at the very earliest stages of development, notably in triggering the gene expression necessary for formation of the eye. It is now timely to test the extent to which connexin hemichannel-mediated ATP release and accompanying Ca(2+) waves contribute to all stages of development.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.