Evidence map›Paper›PMID 18355408›Full record

Trial reportMalaria journal2008

Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda.

Albert Kilian, Wilson Byamukama, Olivier Pigeon, Francis Atieli, Stephan Duchon, Chi Phan

Abstract readClinical Trial, Phase IIIComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 1 synthesis or guideline pooled it.

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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Albert KilianMalaria Consortium, Development House, 56-64 Leonard Street EC2A 4JX, London, UK. a.kilian@malariaconsortium.org
Wilson Byamukama
Olivier Pigeon
Francis Atieli
Stephan Duchon
Chi Phan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn order to evaluate whether criteria for LLIN field performance (phase III) set by the WHO Pesticide Evaluation Scheme are met, first and second generations of one of these products, PermaNet, a polyester net using the coating technology were tested.

methodsA randomized, double blinded study design was used comparing LLIN to conventionally treated nets and following LLIN for three years under regular household use in rural conditions. Primary outcome measures were deltamethrin residue and bioassay performance (60 minute knock-down and 24 hour mortality after a three minute exposure) using a strain of Anopheles gambiae s.s. sensitive to pyrethroid insecticides.

resultsBaseline concentration of deltamethrin was within targets for all net types but was rapidly lost in conventionally treated nets and first generation PermaNet with median of 0.7 and 2.5 mg/m2 after six months respectively. In contrast, second generation PermaNet retained insecticide well and had 41.5% of baseline dose after 36 months (28.7 mg/m2). Similarly, vector mortality and knockdown dropped to 18% and 70% respectively for first generation LLIN after six months but remained high (88.5% and 97.8% respectively) for second generation PermaNet(R) after 36 months of follow up at which time 90.0% of nets had either a knockdown rate > or = 95% or mortality rate > or = 80%.

conclusionSecond generation PermaNet showed excellent results after three years of field use and fulfilled the WHOPES criteria for LLIN. Loss of insecticide on LLIN using coating technology under field conditions was far more influenced by factors associated with handling rather than washing.

Indexed as

AnophelesBedding and LinensMosquito ControlRural HealthAnimalsBiological AssayDouble-Blind MethodFamily CharacteristicsHumansInsecticidesInsect VectorsMalaria, FalciparumNitrilesPolyestersPyrethrinsUgandadecamethrinInsecticidesNitrilesPolyestersPyrethrins

Identifiers

PMID18355408
PMCPMC2330059

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.