Evidence map›Paper›PMID 18353648›Full record

ReviewTrends in microbiology2008

Staying alive: bacterial inhibition of apoptosis during infection.

Christina S Faherty, Anthony T Maurelli

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed.

  1. Article
  2. Article
  3. Parasite-Induced Changes in the Nervous System of the Shore CrabInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Review
  6. bioRxiv : the preprint server for biology · 2025
    Article
  7. Microorganisms · 2025
    Article
  8. Cell Death and Infection: Implications for Host and Microbe.Advances in experimental medicine and biology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Vaccines · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christina S FahertyDepartment of Microbiology and Immunology, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814-4799, USA.
Anthony T Maurelli

Funding

TEMPERATURE REGULATION OF SHIGELLA VIRULENCE GENESR01AI024656 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI MAURELLI, ANTHONY T · 1989 to 2013
$3.8M
NIAID NIH HHS AI24656NIAID NIH HHS R01 AI024656
6 · The paper itself

Abstract

The ability of bacterial pathogens to inhibit apoptosis in eukaryotic cells during infection is an emerging theme in the study of bacterial pathogenesis. Prevention of apoptosis provides a survival advantage because it enables the bacteria to replicate inside host cells. Bacterial pathogens have evolved several ways to prevent apoptosis by protecting the mitochondria and preventing cytochrome c release, by activating cell survival pathways, or by preventing caspase activation. This review summarizes the most recent work on bacterial anti-apoptotic strategies and suggests new research that is necessary to advance the field.

Indexed as

ApoptosisHost-Pathogen InteractionsAnimalsBacteriaBacterial InfectionsCaspase InhibitorsCaspasesCell LineCytochromes cEukaryotic CellsHumansMitochondriaRatsCaspase InhibitorsCaspasesCytochromes c

Identifiers

PMID18353648
PMCPMC2746948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.