ArticlePlanta2008
Transcriptome profiling identified novel genes associated with aluminum toxicity, resistance and tolerance in Medicago truncatula.
Article in Planta, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 127 citations in OpenAlex.
- Aluminum stress responses and beneficial bacterial traits inFrontiers in plant science · 2026Review
- Article
- Effects of Chlortetracycline on Lignin Biosynthesis inInternational journal of molecular sciences · 2025Article
- Transcriptome-based strategies for identifying aluminum tolerance genes in popcorn (Zea mays L. var. everta).Scientific reports · 2023Article
- Identification and expression pattern of aluminium-responsive genes in roots of rice genotype with reference to Al-sensitivity.Scientific reports · 2023Article
- Transcriptome Sequencing ofPlants (Basel, Switzerland) · 2023Article
- Aluminum Stress Induces Irreversible Proteomic Changes in the Roots of the Sensitive but Not the Tolerant Genotype of Triticale Seedlings.Plants (Basel, Switzerland) · 2022Article
- Concepts and considerations for enhancing RNAi efficiency in phytopathogenic fungi for RNAi-based crop protection using nanocarrier-mediated dsRNA delivery systems.Frontiers in fungal biology · 2022Review
- Transcriptomic responses to aluminum stress in tea plant leaves.Scientific reports · 2021Article
- Endomembrane Reorganization Induced by Heavy Metals.Plants (Basel, Switzerland) · 2020Review
- Article
- Overexpression of CrCOMT from Carex rigescens increases salt stress and modulates melatonin synthesis in Arabidopsis thaliana.Plant cell reports · 2019Article
- Molecular Mechanisms of Tungsten Toxicity Differ forFrontiers in plant science · 2019Article
- Article
- Review
- Genome-Wide Association Study Reveals Novel Genomic Regions Associated with 10 Grain Minerals in Synthetic Hexaploid Wheat.International journal of molecular sciences · 2018Article
- Pectin Methylesterases: Cell Wall Remodeling Proteins Are Required for Plant Response to Heat Stress.Frontiers in plant science · 2018Review
- Article
- Plant pectin acetylesterase structure and function: new insights from bioinformatic analysis.BMC genomics · 2017Article
- Morpho-physiological analysis of tolerance to aluminum toxicity in rice varieties of North East India.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oligonucleotide microarrays corresponding to over 16,000 genes were used to analyze changes in transcript accumulation in root tips of the Al-sensitive Medicago truncatula cultivar Jemalong genotype A17 in response to Al treatment. Out of 2,782 genes with significant changes in transcript accumulation, 324 genes were up-regulated and 267 genes were down-regulated at least twofold by Al. Up-regulated genes were enriched in transcripts involved in cell-wall modification and abiotic and biotic stress responses while down-regulated genes were enriched in transcripts involved in primary metabolism, secondary metabolism, protein synthesis and processing, and the cell cycle. Known markers of Al-induced gene expression including genes associated with oxidative stress and cell wall stiffening were differentially regulated in this study. Transcript profiling identified novel genes associated with processes involved in Al toxicity including cell wall modification, cell cycle arrest and ethylene production. Novel genes potentially associated with Al resistance and tolerance in M. truncatula including organic acid transporters, cell wall loosening enzymes, Ca(2+) homeostasis maintaining genes, and Al-binding were also identified. In addition, expression analysis of nine genes in the mature regions of the root revealed that Al-induced gene expression in these regions may play a role in Al tolerance. Finally, interfering RNA-induced silencing of two Al-induced genes, pectin acetylesterase and annexin, in A17 hairy roots slightly increased the sensitivity of A17 to Al suggesting that these genes may play a role in Al resistance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.