Evidence map›Paper›PMID 18350608›Full record

ArticleWorld journal of gastroenterology2008

Endoscopic and histopathological study on the duodenum of Strongyloides stercoralis hyperinfection.

Kazuto Kishimoto, Akira Hokama, Tetsuo Hirata, Yasushix Ihama, Manabu Nakamoto, Nagisa Kinjo, Fukunori Kinjo, Jiro Fujita

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Malabsorption due to strongyloidiasis after high-dose steroid therapy for Coronavirus disease-19.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Article
  7. Article
  8. Rare Complication of Strongyloidiasis in Vietnam: A Case of Venous Thromboembolism and Duodenal Obstruction.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
    Article
  9. A Rare Case ofPathogens (Basel, Switzerland) · 2023
    Article
  10. Article
  11. An unusual case of gastric outlet obstruction and melena.Clinical journal of gastroenterology · 2022
    Article
  12. Review
  13. Article
  14. Eosinophilic appendicitis due toBMJ case reports · 2021
    Article
  15. Image of the month: Target the bugs:Clinical medicine (London, England) · 2021
    Article
  16. Article
  17. Article
  18. Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019
    Review
  19. A bibliometric analysis of human strongyloidiasis research (1968 to 2017).Tropical diseases, travel medicine and vaccines · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kazuto KishimotoDepartment of Endoscopy, Ryukyu University Hospital, Okinawa 903-0215, Japan.
Akira Hokama
Tetsuo Hirata
Yasushix Ihama
Manabu Nakamoto
Nagisa Kinjo
Fukunori Kinjo
Jiro Fujita
University of the Ryukyus · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate endoscopic and histopathological findings in the duodenum of patients with Strongyloides stercoralis (S. stercoralis) hyperinfection.

methodsOver a period of 23 years (1984-2006), we investigated 25 patients with S. stercoralis hyperinfection who had had an esophagogastroduodenoscopy before undergoing treatment for strongyloidiasis. The clinical and endoscopic findings were analyzed retrospectively.

resultsTwenty-four (96%) of the patients investigated were under immunocompromised condition which was mainly due to a human T lymphotropic virus type 1 (HTLV-1) infection. The abnormal endoscopic findings, mainly edematous mucosa, white villi and erythematous mucosa, were observed in 23 (92%) patients. The degree of duodenitis including villous atrophy/destruction and inflammatory cell infiltration corresponded to the severity of the endoscopic findings. The histopathologic yield for identifying larvae was 71.4% by duodenal biopsy. The endoscopic findings of duodenitis were more severe in patients whose biopsies were positive for larvae than those whose biopsies were negative (Endoscopic severity score: 4.86 +/- 2.47 vs 2.71 +/- 1.38, P < 0.05).

conclusionOur study clearly demonstrates that, in addition to stool analysis, endoscopic observation and biopsies are very important. We also emphasize that S. stercoralis and HTLV-1 infections should be ruled out before immunosuppressive therapy is administered in endemic regions.

Indexed as

Endoscopy, Digestive SystemAgedAnimalsBiopsyDuodenitisDuodenumFecesFemaleHTLV-I InfectionsHumansIntestinal MucosaJapanMaleMiddle AgedRetrospective StudiesSeverity of Illness Index

Identifiers

PMID18350608
PMCPMC2695917
OpenAlexW1965340112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.