Evidence map›Paper›PMID 18350354›Full record

ArticleJournal of neurology2008

Pituitary stalk duplication in association with moya moya disease and bilateral morning glory disc anomaly - broadening the clinical spectrum of midline defects.

T Loddenkemper, N R Friedman, P M Ruggieri, A Marcotty, J Sears, E I Traboulsi

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Morning Glory Disc Anomaly: Expanding the MR Phenotype.AJNR. American journal of neuroradiology · 2024
    Article
  2. Article
  3. Review
  4. Review
  5. Hypophyseal triplication: case report and embryologic considerations.AJNR. American journal of neuroradiology · 2009
    Article
  6. Cavitary anomalies of the optic disc: neurologic significance.Current neurology and neuroscience reports · 2008
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

T LoddenkemperDept. of Neurology, The Cleveland Clinic Foundation, 9500 Euclid Ave, S-71, Cleveland, OH 44195, USA. loddent@ccf.org
N R Friedman
P M Ruggieri
A Marcotty
J Sears
E I Traboulsi
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuplication of the pituitary stalk, morning glory disc anomaly and moya moya are rare malformations. The combination of these findings may be syndromic and may have an underlying genetic etiology.

methodsCase report and review of the literature of neurological, ophthalmological, and neuroradiological findings including ophthalmic examination, MRI and MRA. CASE REPORT: A 2 year-old girl presented with reduced visual acuity and roving eye movements since birth. Ophthalmological workup revealed bilateral morning glory disc anomaly. MRI showed duplication of the pituitary stalk and caudal displacement of the floor of the third ventricle. MRA showed narrowing of the supraclinoid internal carotid arteries with focal narrowing of the proximal middle cerebral arteries consistent with early moya moya disease.

conclusionsReview of the literature of pituitary gland duplication and of the combination of morning glory disc anomaly and moya moya disease revealed only one previously reported case. However, the spectrum of this possibly syndromic presentation may be much broader and include various types of anterior midline defects and may have a common underlying genetic cause.

Indexed as

Carotid Artery, InternalCerebral ArteriesChild, PreschoolDisease ProgressionFemaleHumansMagnetic Resonance AngiographyMagnetic Resonance ImagingMiddle Cerebral ArteryMoyamoya DiseaseNervous System MalformationsOptic DiskPituitary GlandRetinaRetinal ArteryThird Ventricle

Identifiers

PMID18350354
OpenAlexW1984798846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.