ArticleNucleic acids research1991
Polypeptide components of Drosophila small nuclear ribonucleoprotein particles.
Article in Nucleic acids research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Prp8 protein: at the heart of the spliceosome.RNA (New York, N.Y.) · 2005Review
- In situ transcription and splicing in the Balbiani ring 3 gene.The EMBO journal · 2001Article
- Purification of Drosophila snRNPs and characterization of two populations of functional U1 particles.RNA (New York, N.Y.) · 2001Article
- Association of the neuron-specific RNA binding domain-containing protein ELAV with the coiled body in Drosophila neurons.Chromosoma · 1997Article
- Sex-lethal interacts with splicing factors in vitro and in vivo.Molecular and cellular biology · 1996Article
- Extensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.The EMBO journal · 1995Article
- Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing.Nucleic acids research · 1995Article
- Assembly and disassembly of spliceosomes along a specific pre-messenger RNP fiber.The EMBO journal · 1994Article
- Yeast protein splicing factors involved in nuclear pre-mRNA splicing.Molecular biology reports · 1993Review
- Protein composition of mammalian spliceosomal snRNPs.Molecular biology reports · 1993Review
- Association of individual hnRNP proteins and snRNPs with nascent transcripts.The Journal of cell biology · 1993Article
- Roles of PRP8 protein in the assembly of splicing complexes.The EMBO journal · 1992Article
- Splicing signals in Drosophila: intron size, information content, and consensus sequences.Nucleic acids research · 1992Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In eukaryotes splicing of pre-mRNAs is mediated by the spliceosome, a dynamic complex of small nuclear ribonucleoprotein particles (snRNPs) that associate transiently during spliceosome assembly and the splicing reaction. We have purified snRNPs from nuclear extracts of Drosophila cells by affinity chromatography with an antibody specific for the trimethylguanosine (m3G) cap structure of snRNAs U1-U5. The polypeptide components of Drosophila snRNPs have been characterized and shown to consist of a number of proteins shared by all the snRNPs, and some proteins which appear to be specific to individual snRNP particles. On the basis of their apparent molecular weight and antigenicity many of these common and particle specific Drosophila snRNP proteins are remarkably conserved between Drosophila and human spliceosomes. By probing western blots of the Drosophila snRNP polypeptides with a number of antisera raised against human snRNP proteins, Drosophila polypeptides equivalent to many of the HeLa snRNP-common proteins have been identified, as well as candidates for a number of U1, U2 and U5-specific proteins.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.