ArticleLipids in health and disease2008
Can essential fatty acids reduce the burden of disease(s)?
Article in Lipids in health and disease, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 77 citations in OpenAlex.
- Biochemical profile ofFood science & nutrition · 2024Article
- Hydrolysis of Edible Oils by Fungal Lipases: An Effective Tool to Produce Bioactive Extracts with Antioxidant and Antimicrobial Potential.Foods (Basel, Switzerland) · 2022Article
- Beneficial Actions of Essential Fatty Acids in Streptozotocin-Induced Type 1 Diabetes Mellitus.Frontiers in nutrition · 2022Article
- Potential Dietary Interventions for COVID-19 Infection Based on the Gut-Immune Axis: An Update Review on Bioactive Component of Macronutrients.International journal of preventive medicine · 2021Review
- Article
- Association between Plasma N-6 Polyunsaturated Fatty Acids Levels and the Risk of Cardiovascular Disease in a Community-based Cohort Study.Scientific reports · 2019Article
- Implications of telomeres and telomerase in endometrial pathology.Human reproduction update · 2017Review
- Standardized Chinese Formula Xin-Ke-Shu inhibits the myocardium Ca(2+) overloading and metabolic alternations in isoproterenol-induced myocardial infarction rats.Scientific reports · 2016Article
- Deregulated balance of omega-6 and omega-3 polyunsaturated fatty acids following infection by the zoonotic pathogen Streptococcus suis.Infection and immunity · 2014Article
- Maternal dietary DHA supplementation to improve inflammatory outcomes in the preterm infant.Advances in nutrition (Bethesda, Md.) · 2012Article
- Multiple roles of dihomo-γ-linolenic acid against proliferation diseases.Lipids in health and disease · 2012Review
- Inhibitory potential of omega-3 fatty and fenugreek essential oil on key enzymes of carbohydrate-digestion and hypertension in diabetes rats.Lipids in health and disease · 2011Article
- Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors.Cancer metastasis reviews · 2011Review
- Effect of ω-3 and ω-9 fatty acid rich oils on lipoxygenases and cyclooxygenases enzymes and on the growth of a mammary adenocarcinoma model.Lipids in health and disease · 2010Article
- Current and emerging strategies for the treatment and management of systemic lupus erythematosus based on molecular signatures of acute and chronic inflammation.Journal of inflammation research · 2010Article
- Correlation of omega-3 levels in serum phospholipid from 2053 human blood samples with key fatty acid ratios.Nutrition journal · 2009Article
- Resolvins and protectins: mediating solutions to inflammation.British journal of pharmacology · 2009Review
- Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules.Lipids in health and disease · 2008Review
- Can endogenous lipid molecules serve as predictors and prognostic markers of coronary heart disease?Lipids in health and disease · 2008Article
- Effectiveness of omega-3 polyunsaturated fatty acids against microbial pathogens.Journal of Zhejiang University. Science. BReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronary heart disease, stroke, diabetes mellitus, hypertension, cancer, depression schizophrenia, Alzheimer's disease, and collagen vascular diseases are low-grade systemic inflammatory conditions that are a severe burden on health care resources. Essential fatty acids (EFAs) and their metabolites: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), gamma-linolenic acid (GLA), dihomo-gamma-linolenic acid (DGLA), and arachidonic acid (AA) and their products: prostaglandin E1, prostacyclin, lipoxins, resolvins, and protectins suppress inflammation, augment healing, and are of benefit in the prevention and management of these conditions. Hence, supplementation of EFAs could reduce burden of these disease(s).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.