ReviewNeuropsychology review2008
Neuropsychological contributions to the early identification of Alzheimer's disease.
Review in Neuropsychology review, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04185298 (Mobile Technology-Based Simultaneous Aerobic Exercise and Memory Training Intervention for Older Adults With Mild Cognitive Impairment), which is not on this map. Cited by 92 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mobile Technology-Based Simultaneous Aerobic Exercise and Memory Training Intervention for Older Adults With Mild Cognitive Impairment
Who cites it
92 citing papers in PubMed.
- Multimedia Aided Consent for Alzheimer's Disease Research.Clinical gerontologistTrial
- Neuropsychological criteria for Mild Cognitive Impairment (MCI) best identify neuroimaging-based risk profiles: A Department of Defense/Alzheimer's Disease Neuroimaging Initiative study.Journal of the International Neuropsychological Society : JINS · 2026Article
- Accelerated long-term forgetting as a predictor of clinical onset in presymptomatic autosomal dominant Alzheimer's disease.Journal of neurology, neurosurgery, and psychiatry · 2026Article
- Subtle inefficiencies in everyday tasks indicate early functional difficulties in older adults: Implications for clinical practice and research.The Clinical neuropsychologist · 2026Article
- Cognitive performance among diverse Asian American subgroups: exploring the role of nativity, language, and education.NPJ dementia · 2026Article
- Age differences in spatial navigation stem from a preference for familiar routes rather than impaired landmark-dependent strategies.Psychology and aging · 2025Article
- A novel approach hybrid of ensemble learning and 3-D CNN mechanism: early-stage diagnosis of Alzheimer's disease using EEG signals.Scientific reports · 2025Article
- Using neuropsychological test scores to predict beta-amyloid deposition in older adults across the late-life cognitive continuum.Journal of clinical and experimental neuropsychology · 2025Article
- Neuronal and glial dysfunction, white matter hyperintensities and cognition in ageing and Alzheimer's disease.Brain communications · 2025Article
- Cortical Surface Area Profile Mediates Effects of Childhood Disadvantage on Later-Life General Cognitive Ability.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Differentiating Alzheimer's disease from mild cognitive impairment: a quick screening tool based on machine learning.BMJ open · 2023Article
- Genetic and Environmental Influences on Structural and Diffusion-Based Alzheimer's Disease Neuroimaging Signatures Across Midlife and Early Old Age.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Higher cortical thickness/volume in Alzheimer's-related regions: protective factor or risk factor?Neurobiology of aging · 2023Article
- Diminished activation of excitatory neurons in the prelimbic cortex leads to impaired working memory capacity in mice.BMC biology · 2023Article
- Cognitive reserve moderates the association between cerebral blood flow and language performance in older adults with mild cognitive impairment.Neurobiology of aging · 2023Article
- Entorhinal cortex dysfunction in Alzheimer's disease.Trends in neurosciences · 2023Review
- Midlife Neuropsychological Profiles and Associated Vascular Risk: The Bogalusa Heart Study.Journal of Alzheimer's disease : JAD · 2023Article
- Blood-Derived Progenitor Cells Are Depleted in Older Adults with Cognitive Impairment: A Role for Vascular Resilience?Journal of Alzheimer's disease : JAD · 2023Article
- Cognitive Decline Associated with Aging.Advances in experimental medicine and biology · 2023Article
- Prevalence and Patterns of Cognitive Impairment in a Sample of Community Dwelling Older People in Nigeria.JAR life · 2023Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
A wealth of evidence demonstrates that a prodromal period of Alzheimer's disease (AD) exists for some years prior to the appearance of significant cognitive and functional declines required for the clinical diagnosis. This prodromal period of decline is characterized by a number of different neuropsychological and brain changes, and reliable identification of individuals prior to the development of significant clinical symptoms remains a top priority of research. In this review we provide an overview of those neuropsychological changes. In particular, we examine specific domains of cognition that appear to be negatively affected during the prodromal period of AD, and we review newer analytic strategies designed to examine cognitive asymmetries or discrepancies between higher-order cognitive functions versus fundamental skills. Finally, we provide a critical examination of the clinical concept of Mild Cognitive Impairment and offer suggestions for an increased focus on the impact of cerebrovascular disease (CVD) and CVD risk during the prodromal period of AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.