ReviewHeart failure reviews2008
Intracellular devastation in heart failure.
Review in Heart failure reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- The role of cardiac microenvironment in cardiovascular diseases: implications for therapy.Human cell · 2024Review
- Protective effects of GαNaunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Reduced mitochondrial pyruvate carrier expression in hearts with heart failure and reduced ejection fraction patients: ischemic vs. non-ischemic origin.Frontiers in cardiovascular medicine · 2024Article
- SERCA2 phosphorylation at serine 663 is a key regulator of CaNature communications · 2023Article
- Heart and Brain: Complex Relationships for Left Ventricular Dysfunction.Current cardiology reports · 2020Review
- Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure.Circulation research · 2019Review
- Dysregulation of intracellular calcium transporters in animal models of sepsis-induced cardiomyopathy.Shock (Augusta, Ga.) · 2015Review
- Rethinking cardiac metabolism: metabolic cycles to refuel and rebuild the failing heart.F1000prime reports · 2014Review
- Abnormal calcium handling and exaggerated cardiac dysfunction in mice with defective vitamin d signaling.PloS one · 2014Article
- Article
- Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure.The Annals of thoracic surgery · 2013Article
- Benefit of SERCA2a gene transfer to vascular endothelial and smooth muscle cells: a new aspect in therapy of cardiovascular diseases.Current vascular pharmacology · 2013Review
- An improved isolation procedure for adult mouse cardiomyocytes.Cell biochemistry and biophysics · 2011Article
- Endoplasmic-reticulum calcium depletion and disease.Cold Spring Harbor perspectives in biology · 2011Review
- Redox signaling in cardiac myocytes.Free radical biology & medicine · 2011Review
- MicroRNAs--regulators of signaling networks in dilated cardiomyopathy.Journal of cardiovascular translational research · 2010Review
- Protein aggregates and novel presenilin gene variants in idiopathic dilated cardiomyopathy.Circulation · 2010Article
- Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure.Expert opinion on biological therapy · 2010Review
- Identification of a cardiac disease modifier gene using forward genetics in the mouse.PLoS genetics · 2009Article
- Structure and functional analysis of a Ca2+ sensor mutant of the Na+/Ca2+ exchanger.The Journal of biological chemistry · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
End-stage heart failure is characterized by a number of abnormalities at the cellular level, which include changes in excitation-contraction coupling, alterations in contractile proteins and activation/deactivation of signaling pathways. Even though many of these changes are adaptive to the high workload and stress in heart failure, a significant number of these alterations are deeply deleterious to the cardiac cell. In this article, we will review the changes in calcium cycling that occur in myopathic hearts and how they can be effectively targeted. We will also focus on protein misfolding in the setting of cardiac dysfunction.
Indexed as
Identifiers
18347978What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.