Evidence map›Paper›PMID 18347928›Full record

ArticleCell and tissue banking2008

The Sun Health Research Institute Brain Donation Program: description and experience, 1987-2007.

Thomas G Beach, Lucia I Sue, Douglas G Walker, Alex E Roher, LihFen Lue, Linda Vedders, Donald J Connor, Marwan N Sabbagh, Joseph Rogers

Abstract readHistorical Article
In one paragraph

Article in Cell and tissue banking, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 212 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
212citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

212 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Brain donation rules in Italy and worldwide: overview of a cutting-edge topic for human brain research.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  12. An analysis of RNA quality metrics in human brain tissue.Journal of neuropathology and experimental neurology · 2025
    Article
  13. Article
  14. Article
  15. Article
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  19. Conjugal Synucleinopathies: A Clinicopathologic Study.Movement disorders : official journal of the Movement Disorder Society · 2024
    Article
  20. Article

152 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas G BeachSun Health Research Institute, Sun City, 85351, USA. thomas.beach@sunhealth.org
Lucia I Sue
Douglas G Walker
Alex E Roher
LihFen Lue
Linda Vedders
Donald J Connor
Marwan N Sabbagh
Joseph Rogers

Funding

Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI GONZALEZ HERNANDEZ, GRACIELA · 2001 to 2020
$32.5M
NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG19610
6 · The paper itself

Abstract

The Brain Donation Program at Sun Health Research Institute has been in continual operation since 1987, with over 1000 brains banked. The population studied primarily resides in the retirement communities of northwest metropolitan Phoenix, Arizona. The Institute is affiliated with Sun Health, a nonprofit community-owned and operated health care provider. Subjects are enrolled prospectively to allow standardized clinical assessments during life. Funding comes primarily from competitive grants. The Program has made short postmortem brain retrieval a priority, with a 2.75-h median postmortem interval for the entire collection. This maximizes the utility of the resource for molecular studies; frozen tissue from approximately 82% of all cases is suitable for RNA studies. Studies performed in-house have shown that, even with very short postmortem intervals, increasing delays in brain retrieval adversely affect RNA integrity and that cerebrospinal fluid pH increases with postmortem interval but does not predict tissue viability.

Indexed as

Academies and InstitutesBrainTissue and Organ ProcurementTissue BanksArizonaDatabases, Nucleic AcidHistory, 20th CenturyHistory, 21st CenturyHumansPostmortem ChangesTissue DonorsTissue PreservationTissue Survival

Identifiers

PMID18347928
PMCPMC2493521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.