Trial reportCancer causes & control : CCC2008
History of benign breast disease and risk of breast cancer among women in China: a case-control study.
Trial report in Cancer causes & control : CCC, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Biomarkers of dietary exposure are associated with lower risk of breast fibroadenomas in Chinese women.The Journal of nutrition · 2010Trial
- Breast Cancer Risk Factors Analysis in Middle-Aged Women: Evidence From a Cross-Sectional Epidemiological Study.Health science reports · 2026Article
- The Link BetweenBioMed research international · 2026Article
- Unraveling Benign Breast Conditions: A Comprehensive Study of Diagnosis, Treatment, and Care.Cureus · 2025Article
- Circulating miRNA-373 and Vascular Endothelial Growth Factor as Potential Biomarkers for Early Detection of Breast Cancer.Indian journal of clinical biochemistry : IJCB · 2024Article
- Benign breast disease and breast cancer risk in African women: a case-control study.Cancer causes & control : CCC · 2024Article
- Benign Breast Disease and Breast Cancer Risk in the Percutaneous Biopsy Era.JAMA surgery · 2024Article
- Article
- Analysis of risk factors associated with breast cancer in women: a systematic review and meta-analysis.Translational cancer research · 2022Article
- Family History, Reproductive, and Lifestyle Risk Factors for Fibroadenoma and Breast Cancer.JNCI cancer spectrum · 2018Article
- Do Breast Cancer Risk Factors Affect the Survival of Breast Cancer Patients in Southern Sri Lanka?Asian Pacific journal of cancer prevention : APJCP · 2017Article
- Associations of reproductive time events and intervals with breast cancer risk: a report from the Shanghai Breast Cancer Study.International journal of cancer · 2014Article
- Expression of leukemia/lymphoma-related factor (LRF/POKEMON) in human breast carcinoma and other cancers.Experimental and molecular pathology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundData from the Shanghai Breast Cancer Study were analyzed to evaluate the relationship between benign breast disease (BBD) and breast cancer among Chinese women with a self-report of physician-diagnosed BBD.
methodsStudy participants consisted of 3,452 breast cancer cases and 3,474 population controls recruited by the Shanghai Breast Cancer Study. In-person interviews were conducted to collect information on demographics and suspected risk factors for breast cancer, including a detailed history of BBD. Unconditional logistic regression was used to derive adjusted odds ratios (OR(adj)) and 95% confidence intervals (CI) for the association between self-reported BBD and breast cancer.
resultsWomen with breast cancer were significantly more likely to have a self-reported history of BBD including lobular proliferation (OR(adj) = 1.6; 95% CI 1.4-1.8), fibroadenoma (OR(adj) = 1.9; 95% CI 1.6-2.3), and other BBD (OR(adj) = 1.6; 95% CI 1.3-2.1). Breast cancer risk was lower for surgically treated fibroadenoma as compared to non-surgically treated and higher for other BBDs that were surgically treated versus non-surgically treated.
conclusionsOur results suggest that personal history of BBD is associated with an increased risk of future breast cancer among women in China. Surgical intervention for fibroadenoma may reduce the risk.
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