Evidence map›Paper›PMID 18347592›Full record

ReviewNature reviews. Genetics2008

Comparing whole genomes using DNA microarrays.

David Gresham, Maitreya J Dunham, David Botstein

Abstract readComparative StudyReview
In one paragraph

Review in Nature reviews. Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Genes · 2023
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David GreshamLewis-Sigler Institute for Integrative Genomics, Department of Molecular Biology, Carl Icahn Laboratory, Princeton University, Princeton, New Jersey 08544, USA. dgresham@genomics.princeton.edu
Maitreya J Dunham
David Botstein

Funding

Spatial Patterning During DevelopmentP50GM071508 · NIGMS · PRINCETON UNIVERSITY · PI POWELL, SUSAN M · 2004 to 2013
$30.6M
Genetics of Functional Interactions in YeastR01GM046406 · NIGMS · STANFORD UNIVERSITY · PI BOTSTEIN, DAVID · 2001 to 2015
$9.5M
Regulation of Quiescence in Eukaryotic CellsR01GM107466 · NIGMS · NEW YORK UNIVERSITY · PI GRESHAM, DAVID · 2013 to 2022
$3.0M
NIGMS NIH HHS GM-071508NIGMS NIH HHS P50 GM071508NIGMS NIH HHS R01 GM046406NIGMS NIH HHS R01 GM107466
6 · The paper itself

Abstract

The rapid accumulation of complete genomic sequences offers the opportunity to carry out an analysis of inter- and intra-individual genome variation within a species on a routine basis. Sequencing whole genomes requires resources that are currently beyond those of a single laboratory and therefore it is not a practical approach for resequencing hundreds of individual genomes. DNA microarrays present an alternative way to study differences between closely related genomes. Advances in microarray-based approaches have enabled the main forms of genomic variation (amplifications, deletions, insertions, rearrangements and base-pair changes) to be detected using techniques that are readily performed in individual laboratories using simple experimental approaches.

Indexed as

Genetic VariationGenomeOligonucleotide Array Sequence AnalysisAnimalsChromosome MappingGene DosageGenomicsHumansPolymorphism, Single Nucleotide

Identifiers

PMID18347592
PMCPMC7097741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.