ArticleGenes & development2008
Auxin influx carriers stabilize phyllotactic patterning.
Article in Genes & development, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.
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Who cites it
122 citing papers in PubMed, 272 citations in OpenAlex.
- Single-nucleus transcriptomics resolves multiple fate dynamics between inflorescence meristem and primary stem.Science advances · 2026Article
- Auxin Biosynthesis, Transport, Signaling, and Its Roles in Plant Leaf Morphogenesis.Plants (Basel, Switzerland) · 2025Review
- Differential Alteration of Gene Expression by Benzyl Adenine andPlants (Basel, Switzerland) · 2025Article
- Exploring the role of BpPIN3 in hormonal regulation and branching morphogenesis of Betula pendula.BMC plant biology · 2025Article
- Structural basis of auxin binding and transport byProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Structures and mechanism of the AUX/LAX transporters involved in auxin import.Nature plants · 2025Article
- Transcriptomic analysis of wrinkled leaf development of Tai-cai (Brassica rapa var. tai-tsai) and its synthetic allotetraploid via RNA and miRNA sequencing.Plant molecular biology · 2025Article
- Identity Transitions of Tapetum Phases: Insights into Vesicular Dynamics and in Mortem Support During Pollen Maturation.Plants (Basel, Switzerland) · 2025Review
- Slow release of a synthetic auxin induces formation of adventitious roots in recalcitrant woody plants.Nature biotechnology · 2024Article
- Molecular Manipulation of the miR160/Genes · 2024Article
- Multiplexed in situ hybridization reveals distinct lineage identities for major and minor vein initiation during maize leaf development.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Auxin and abiotic stress responses.Journal of experimental botany · 2023Review
- Characterization of the Molecular Events Underlying the Establishment of Axillary Meristem Region in Pepper.International journal of molecular sciences · 2023Article
- Endogenous auxin maintains embryonic cell identity and promotes somatic embryo development in Arabidopsis.The Plant journal : for cell and molecular biology · 2023Article
- Transcriptomic Evidence Reveals Low Gelatinous Layer Biosynthesis inInternational journal of molecular sciences · 2022Article
- Regulators of early maize leaf development inferred from transcriptomes of laser capture microdissection (LCM)-isolated embryonic leaf cells.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Pleiotropic and nonredundant effects of an auxin importer in Setaria and maize.Plant physiology · 2022Article
- Functional Characterization ofInternational journal of molecular sciences · 2022Article
- Auxin Transporters-A Biochemical View.Cold Spring Harbor perspectives in biology · 2022Review
- Genome-wide identification and expression analysis ofFrontiers in plant science · 2022Article
62 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most striking features of plant architecture is the regular arrangement of leaves and flowers around the stem, known as phyllotaxis. Peaks in concentration of the plant hormone auxin, generated by the polar localization of the PIN1 auxin efflux carrier, provide the instructive signal for primordium initiation. This mechanism generates the spacing between neighboring primordia, which results in regular phyllotaxis. Studies of the role of auxin transport in phyllotactic patterning have focused on PIN1-mediated efflux. Recent computer simulations indicate an additional role for transporter-mediated auxin uptake. Mutations in the AUX1 auxin influx carrier have not, however, been reported to cause an aerial phenotype. Here, we study the role of AUX1 and its paralogs LAX1, LAX2, and LAX3. Analysis of the quadruple mutant reveals irregular divergence angles between successive primordia. A highly unusual aspect of the phenotype is the occurrence of clusters of primordia, in violation of classical theory. At the molecular level, the sharp peaks in auxin levels and coordinated PIN polarization are reduced or lost. In addition, the increased penetrance of the phenotype under short-day conditions suggests that the AUX LAX transporters act to buffer the PIN-mediated patterning mechanism against environmental or developmental influences.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.