Evidence map›Paper›PMID 18344007›Full record

Trial reportCancer causes & control : CCC2008

Unpasteurized milk consumption and subsequent risk of cancer.

Thomas A Sellers, Robert A Vierkant, Julie Djeu, Esteban Celis, Alice H Wang, Nagi Kumar, James R Cerhan

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer causes & control : CCC, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification of bovine leukemia virus in raw milk samples in North-West of Iran.Veterinary research forum : an international quarterly journal · 2021
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thomas A SellersH. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA. Thomas.Sellers@Moffitt.org
Robert A Vierkant
Julie Djeu
Esteban Celis
Alice H Wang
Nagi Kumar
James R Cerhan
Moffitt Cancer Center · USMayo Clinic · US

Funding

EPIDEMIOLOGY OF CANCER IN A COHORT OF OLDER WOMENR01CA039742 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LAZOVICH, DEANN · 1985 to 2014
$8.0M
NCI NIH HHS R01 CA039742NCI NIH HHS R01CA39742
6 · The paper itself

Abstract

Concerns have been raised regarding the possible adverse health effects of consumption of unpasteurized milk and risk of cancer. We examined the association of self-reported intake of unpasteurized milk with subsequent risk of cancer in a large population-based cohort study. The Iowa Women's Health Study is a prospective cohort study of 55-69 year old women at baseline in 1986. Of the 41,836 women in the cohort at baseline, 22,808 cancer-free women completed the fourth follow-up questionnaire in 1997. Risk ratios (RR) and 95% confidence intervals (CI) were calculated using Cox proportional hazards regression analysis. Reported intake of unpasteurized milk was high: 59.2% consumed only as a child, 2.5% consumed only as an adult, and 16.5% consumed as a child and an adult. A total of 2,379 cancers were identified in the cohort at risk. Overall, the age-adjusted risk of cancer was lower among women who reported consumption of unpasteurized milk only as a child (RR = 0.90, 95% CI: 0.82-0.99) or as a child and an adult (RR = 0.85; 95% CI: 0.75-0.97). Adjustment for confounding factors attenuated these associations (RR = 0.92, 95% CI: 0.83-1.02 for consumption only as a child, and RR = 0.91; 95% CI: 0.79-1.04 for consumption as a child and an adult). These data suggest that consumption of unpasteurized milk does not increase risk of cancer.

Indexed as

DietMilkAgedAnimalsCohort StudiesFemaleHumansIncidenceMaleMiddle AgedNeoplasmsProspective StudiesRisk AssessmentSurveys and Questionnaires

Identifiers

PMID18344007
PMCPMC2575230
OpenAlexW1981654411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.