Evidence map›Paper›PMID 18342599›Full record

ArticleMolecular cell2008

"Unraveling the tail" of how SRPK1 phosphorylates ASF/SF2.

Daniel Y L Mao, Derek F Ceccarelli, Frank Sicheri

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Daniel Y L MaoProgram in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada.
Derek F Ceccarelli
Frank Sicheri
Mount Sinai Hospital · CAUniversity of New Brunswick · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Molecular Cell, Ngo et al. (2008) describe the crystal structure of the SRPK1 protein kinase in complex with its substrate, the spliceosome factor ASF/SF2, providing an unprecedented view of multiple targeting mechanisms in action on a single substrate.

Indexed as

Protein Structure, TertiaryAnimalsHumansMiceNuclear ProteinsPhosphorylationProtein Serine-Threonine KinasesRNA-Binding ProteinsSerine-Arginine Splicing FactorsSubstrate SpecificityNuclear ProteinsProtein Serine-Threonine KinasesRNA-Binding ProteinsSerine-Arginine Splicing FactorsSRPK1 protein, human

Identifiers

PMID18342599
OpenAlexW1990529394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.