ArticleJournal of substance abuse treatment2008
Comparison of cannabis and tobacco withdrawal: severity and contribution to relapse.
Article in Journal of substance abuse treatment, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of Cannabis Withdrawal Symptoms Among People With Regular or Dependent Use of Cannabinoids: A Systematic Review and Meta-analysis.JAMA network open · 2020Pooled it
- Behavioral therapies for treatment-seeking cannabis users: a meta-analysis of randomized controlled trials.Evaluation & the health professions · 2015Pooled it
- The effect of daily aerobic cycling exercise on cannabis withdrawal: An inpatient randomised controlled trial.Scientific reports · 2026Trial
- Randomized controlled trial of zolpidem as a pharmacotherapy for cannabis use disorder.Journal of substance use and addiction treatment · 2024Trial
- Cognitive behavioral therapy for insomnia to reduce cannabis use: Results from a pilot randomized controlled trial.Drug and alcohol dependence · 2023Trial
- Trial
- Effects of cannabis use on alcohol consumption in a sample of treatment-engaged heavy drinkers in Colorado.Addiction (Abingdon, England) · 2021Trial
- Nicotine patch for cannabis withdrawal symptom relief: a randomized controlled trial.Psychopharmacology · 2020Trial
- Current cannabis use and smoking cessation among treatment seeking combustible smokers.Drug and alcohol dependence · 2020Trial
- Repetitive transcranial magnetic stimulation (rTMS) administration to heavy cannabis users.The American journal of drug and alcohol abuse · 2018Trial
- Effects of zolpidem alone and in combination with nabilone on cannabis withdrawal and a laboratory model of relapse in cannabis users.Psychopharmacology · 2016Trial
- Effects of fixed or self-titrated dosages of Sativex on cannabis withdrawal and cravings.Drug and alcohol dependence · 2016Trial
- The Effects of Lithium Carbonate Supplemented with Nitrazepam on Sleep Disturbance during Cannabis Abstinence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015Trial
- Do withdrawal-like symptoms mediate increased marijuana smoking in individuals treated with venlafaxine-XR?Drug and alcohol dependence · 2014Trial
- A human laboratory study investigating the effects of quetiapine on marijuana withdrawal and relapse in daily marijuana smokers.Addiction biology · 2013Trial
- The dose effects of short-term dronabinol (oral THC) maintenance in daily cannabis users.Drug and alcohol dependence · 2013Trial
- A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Trial
- Characterizing smoking topography of cannabis in heavy users.Psychopharmacology · 2012Trial
- Sleep disturbance and the effects of extended-release zolpidem during cannabis withdrawal.Drug and alcohol dependence · 2011Trial
- Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trial.Drug and alcohol dependence · 2011Trial
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This naturalistic telephone survey study compared perceptions of withdrawal severity in 67 daily cannabis users and 54 daily tobacco cigarette smokers who made quit attempts during the prior 30 days. A Withdrawal Symptom Checklist assessed the severity of abstinence symptoms and a Likert scale assessed perceived relations between abstinence symptoms and relapse. A composite Withdrawal Discomfort Score did not differ significantly between groups (M = 13.0 for cannabis, vs. M = 13.2 for tobacco). Individual symptom severity ratings were also of similar magnitude, except craving and sweating were slightly higher for tobacco. Both groups reported that withdrawal contributed substantially to relapse, and the strength of these ratings was similar across groups. The diverse convenience sample examined in this study adds external validity and generalizability to prior studies that included only users not planning to quit or excluded many common types of cannabis users. The comparable withdrawal experience from these heterogeneous cannabis and tobacco users supports previous findings from controlled laboratory studies and indicates that real-world, frequent cannabis users perceive that withdrawal symptoms negatively affect their desire and ability to quit.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.