ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2008
Single molecule measurements and molecular motors.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 34 citations in OpenAlex.
- Clocked stepping of an artificial protein walker along a DNA track.Nature nanotechnology · 2026Article
- Structure of actomyosin rigour complex at 5.2 Å resolution and insights into the ATPase cycle mechanism.Nature communications · 2017Article
- Local heating of molecular motors using single carbon nanotubes.Biophysical reviews · 2016Review
- Optical trapping of individual human immunodeficiency viruses in culture fluid reveals heterogeneity with single-molecule resolution.Nature nanotechnology · 2014Article
- Switching of myosin-V motion between the lever-arm swing and brownian search-and-catch.Nature communications · 2012Article
- Lever-arm mechanics of processive myosins.Biophysical journal · 2011Review
- Gene transfer, expression, and sarcomeric incorporation of a headless myosin molecule in cardiac myocytes: evidence for a reserve in myofilament motor function.American journal of physiology. Heart and circulatory physiology · 2011Article
- Article
- Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis.Nature reviews. Molecular cell biology · 2010Review
- Introduction. Japan: its tradition and hot topics in biological sciences.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2008Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Single molecule imaging and manipulation are powerful tools in describing the operations of molecular machines like molecular motors. The single molecule measurements allow a dynamic behaviour of individual biomolecules to be measured. In this paper, we describe how we have developed single molecule measurements to understand the mechanism of molecular motors. The step movement of molecular motors associated with a single cycle of ATP hydrolysis has been identified. The single molecule measurements that have sensitivity to monitor thermal fluctuation have revealed that thermal Brownian motion is involved in the step movement of molecular motors. Several mechanisms have been suggested in different motors to bias random thermal motion to directional movement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.