ReviewLa Radiologia medica2008
MR spectroscopy of the breast.
Review in La Radiologia medica, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 57 citations in OpenAlex.
- Article
- Changes in total choline concentration in the breast of healthy fertile young women in relation to menstrual cycle or use of oral contraceptives: a 3-TEuropean radiology experimental · 2018Article
- Proton and phosphorus magnetic resonance spectroscopy of the healthy human breast at 7 T.NMR in biomedicine · 2017Article
- The potential of multiparametric MRI of the breast.The British journal of radiology · 2017Review
- [Multiparametric and molecular imaging of breast tumors with MRI and PET/MRI].Der Radiologe · 2016Review
- Clinical Breast MR Using MRS or DWI: Who Is the Winner?Frontiers in oncology · 2016Review
- Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies.Cancer biology & medicine · 2014Review
- 3.0 T proton magnetic resonance spectroscopy of the liver: quantification of choline.World journal of gastroenterology · 2013Article
- (1)H MR spectroscopy with external reference solution at 1.5 T for differentiating malignant and benign breast lesions: comparison using qualitative and quantitative approaches.European radiology · 2013Article
- In vivo 1H MRS in the assessment of the therapeutic response of breast cancer patients.NMR in biomedicine · 2011Review
- Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.Neoplasia (New York, N.Y.) · 2011Article
- Diffusion-weighted imaging in breast lesion evaluation.La Radiologia medica · 2010Article
- Use of nuclear magnetic resonance-based metabolomics in detecting drug resistance in cancer.Biomarkers in medicine · 2009Article
- Biochemical characterization of breast tumors by in vivo and in vitro magnetic resonance spectroscopy (MRS).Biophysical reviews · 2009Review
- Modern breast cancer detection: a technological review.International journal of biomedical imaging · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This literature review assesses the clinical potential of proton ((1)H) magnetic resonance spectroscopy (MRS) of breast lesions. We here illustrate the basic principles of spectrum acquisition for volumes of interest, determined on the basis of dynamic magnetic resonance imaging (MRI) and of MRS postprocessing. We discuss the criteria for interpreting the spectrum with particular reference to the metabolic significance of the peak of total choline containing compounds at 3.2 ppm, a marker that is correlated with malignancy. We then summarise the findings obtained in lesion characterisation (with a possible gain in specificity with respect to dynamic MRI), the assessment of the effects of neoadjuvant chemotherapy and the correlation reported at high-field between the tumour tissue concentration of choline-containing compounds and the presence of lymph node metastases. Lastly, we outline the clinical use of this technique as the final phase of a complete breast MR examination after intravenous administration of paramagnetic contrast material for the dynamic study, with reference to its use by radiologists dedicated to breast imaging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.