ArticleNucleic acids research1991
Evolutionary conservation of the spliceosomal protein, U2B''.
Article in Nucleic acids research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 31 citations in OpenAlex.
- SNRPB2: a prognostic biomarker and oncogenic driver in esophageal cancer via β-catenin/c-Myc signaling.Frontiers in oncology · 2025Article
- Special Sm core complex functions in assembly of the U2 small nuclear ribonucleoprotein of Trypanosoma brucei.Eukaryotic cell · 2009Article
- Functional redundancy of worm spliceosomal proteins U1A and U2B''.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Genome analysis: RNA recognition motif (RRM) and K homology (KH) domain RNA-binding proteins from the flowering plant Arabidopsis thaliana.Nucleic acids research · 2002Article
- Differential expression of potato U1A spliceosomal protein genes: a rapid method for expression profiling of multigene families.Plant molecular biology · 2001Article
- The movement of coiled bodies visualized in living plant cells by the green fluorescent protein.Molecular biology of the cell · 1999Article
- PRH75, a new nucleus-localized member of the DEAD-box protein family from higher plants.Molecular and cellular biology · 1997Article
- Characterization of a novel arginine/serine-rich splicing factor in Arabidopsis.The Plant cell · 1996Article
- Splicing of precursors to mRNA in higher plants: mechanism, regulation and sub-nuclear organisation of the spliceosomal machinery.Plant molecular biology · 1996Review
- Pre-mRNA splicing in plants: characterization of Ser/Arg splicing factors.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Isolation of a novel RNA-binding protein and its association with a large ribonucleoprotein particle present in the nucleoplasm of tobacco cells.Plant molecular biology · 1996Article
- Molecular characterization of the spliceosomal proteins U1A and U2B" from higher plants.The EMBO journal · 1995Article
- Characterization of a cDNA encoding a novel type of RNA-binding protein in tobacco: its expression and nucleic acid-binding properties.Molecular & general genetics : MGG · 1994Article
- The existence of eukaryotic ribonucleoprotein consensus sequence-type RNA-binding proteins in a prokaryote, Synechococcus 6301.Nucleic acids research · 1994Article
- Characterization and expression of U1snRNA genes from potato.Plant molecular biology · 1992Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
U1 and U2snRNPs play key roles in pre-mRNA splicing. The interactions between the U1 and U2snRNP-specific proteins, U1A, U2A' and U2B'' and their respective UsnRNAs are of interest both to elucidate their roles in splicing, and as models to study RNA-protein interactions. We have cloned a full-length cDNA, encoding U2B'', from potato. This is the first report of a sequence for a plant UsnRNP protein. The plant U2B'' sequence exhibits extensive similarity with the human U2B'' protein at both the DNA and amino acid levels. The evolutionary conservation at the protein level, particularly in sequences implicated in determining specific binding to U2snRNA, suggests conservation of U2B'' function from plants to man. The significance of amino acid substitutions in the RNP-80 motif with respect to U2snRNA binding in plants is discussed.
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