ArticleToxicologic pathology2008
The application of fluorescent quantum dots to confocal, multiphoton, and electron microscopic imaging.
Article in Toxicologic pathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 112 citations in OpenAlex.
- Review
- Quantum Dots: Catalysts for a New Era of Precision Medicine and Biomedical Innovation.Journal of fluorescence · 2026Review
- Immunoelectron microscopy: a comprehensive guide from sample preparation to high-resolution imaging.Discover nano · 2025Review
- Imaging lipid rafts reveals the principle of ApoE4-induced Aβ upregulation in human neurons.iScience · 2025Article
- Advanced Immunomodulatory Biomaterials for Therapeutic Applications.Advanced healthcare materials · 2025Review
- Light-Driven Energy and Charge Transfer Processes between Additives within Electrospun Nanofibres.Molecules (Basel, Switzerland) · 2023Review
- Visualizing Subcellular Localization of a Protein in the Heart using Quantum Dots-Mediated Immuno-Labeling followed by Transmission Electron Microscopy.Journal of visualized experiments : JoVE · 2022Article
- Synthesis of Metal-Organic Frameworks Quantum Dots Composites as Sensors for Endocrine-Disrupting Chemicals.International journal of molecular sciences · 2022Review
- Fluorescent and Electron-Dense Green Color Emitting Nanodiamonds for Single-Cell Correlative Microscopy.Molecules (Basel, Switzerland) · 2020Article
- EGFR Expression in HER2-Driven Breast Cancer Cells.International journal of molecular sciences · 2020Article
- Smart, Tunable CQDs with Antioxidant Properties for Biomedical Applications-Ecofriendly Synthesis and Characterization.Molecules (Basel, Switzerland) · 2020Article
- Towards robust and versatile single nanoparticle fiducial markers for correlative light and electron microscopy.Journal of microscopy · 2019Article
- Quantitative diagnostic imaging of cancer tissues by using phosphor-integrated dots with ultra-high brightness.Scientific reports · 2017Article
- Evaluation of quantum dot conjugated antibodies for immunofluorescent labelling of cellular targets.Beilstein journal of nanotechnology · 2017Article
- Targeted nanodiamonds for identification of subcellular protein assemblies in mammalian cells.PloS one · 2017Article
- Synthesis of Cd-free InP/ZnS Quantum Dots Suitable for Biomedical Applications.Journal of visualized experiments : JoVE · 2016Article
- Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment.Journal of immunology research · 2016Review
- The Importance of CD44 as a Stem Cell Biomarker and Therapeutic Target in Cancer.Stem cells international · 2016Review
- FluoroNanogold: an important probe for correlative microscopy.Journal of chemical biology · 2015Review
- Ultrastructural differences in pretangles between Alzheimer disease and corticobasal degeneration revealed by comparative light and electron microscopy.Acta neuropathologica communications · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Fluorescent quantum dots are emerging as an important tool for imaging cells and tissues, and their unique optical and physical properties have captured the attention of the research community. The most common types of commercially available quantum dots consist of a nanocrystalline semiconductor core composed of cadmium selenide with a zinc sulfide capping layer and an outer polymer layer to facilitate conjugation to targeting biomolecules such as immunoglobulins. They exhibit high fluorescent quantum yields and have large absorption cross-sections, possess excellent photostability, and can be synthesized so that their narrow-band fluorescence emission can occur in a wide spectrum of colors. These properties make them excellent candidates for serving as multiplexing molecular beacons using a variety of imaging modalities including highly correlated microscopies. Whereas much attention has been focused on quantum-dot applications for live-cell imaging, we have sought to characterize and exploit their utility for enabling simultaneous multiprotein immunolabeling in fixed cells and tissues. Considerations for their application to immunolabeling for correlated light and electron microscopic analysis are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.