Evidence map›Paper›PMID 18336941›Full record

ReviewInternational journal of psychophysiology : official journal of the International Organization of Psychophysiology2008

Electrophysiological signatures: magnetoencephalographic studies of the neural correlates of language impairment in autism spectrum disorders.

Timothy P L Roberts, Gwen L Schmidt, Marc Egeth, Lisa Blaskey, Michael M Rey, J Christopher Edgar, Susan E Levy

2 registry-linked trialsOpen access · greenAbstract readComparative StudyReview
In one paragraph

Review in International journal of psychophysiology : official journal of the International Organization of Psychophysiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02746445 completednot on this mapstarted 2016, after this paper: background citation

A Longitudinal Study on the Safety and Efficacy for Subjects With Autism Spectrum Disorder (ASD) Who Received Magnetic EEG/ECG-Guided Resonance Therapy (MeRT)

TypeobservationalSponsorWave NeuroscienceRan2016 to 2017Enrolled11ConditionsAutistic DisorderArmsNo intervention
NCT02758496 completednot on this mapstarted 2016, after this paper: background citation

A Chart Review to Evaluate the Safety and Efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on Subjects With Autism Spectrum Disorder (ASD)

TypeobservationalSponsorWave NeuroscienceRan2016 to 2017Enrolled141ConditionsAutistic DisorderArmsMeRT Efficacy Chart Review
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Auditory processing in noise is associated with complex patterns of disrupted functional connectivity in autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2017
    Article
  10. Article
  11. Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2016
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Longitudinal Heschl's gyrus growth during childhood and adolescence in typical development and autism.Autism research : official journal of the International Society for Autism Research · 2013
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Timothy P L RobertsDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States. robertstim@email.chop.edu
Gwen L Schmidt
Marc Egeth
Lisa Blaskey
Michael M Rey
J Christopher Edgar
Susan E Levy
Children's Hospital of Philadelphia · US

Funding

Training Program in Neurodevelopmental DisabilitiesT32NS007413 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI AMELIA J EISCH, ERIC D MARSH · 1998 to 2026
$8.9M
Electrophysiological Signatures of Language Impairment in Autism Spectrum DisordeR01DC008871 · NIDCD · CHILDREN'S HOSP OF PHILADELPHIA · PI ROBERTS, TIMOTHY P · 2007 to 2018
$3.6M
NIDCD NIH HHS R01 DC008871NIDCD NIH HHS R01DC008871NINDS NIH HHS T32 NS007413NINDS NIH HHS T32NS007413
6 · The paper itself

Abstract

While magnetoencephalography (MEG) is of increasing utility in the assessment of pediatric patients with seizure disorders, this reflects only a part of the clinical potential of the technology. Beyond epilepsy, a broad range of developmental psychiatric disorders require the spatial and temporal resolution of brain activity offered by MEG. This article reviews the application of MEG in the study of auditory processing as an aspect of language impairment in children. Specifically, the potential application of MEG is elaborated in autism spectrum disorders (ASD), a devastating disorder with prevalence of 1 in 150. Results demonstrate the sensitivity of MEG for detection of abnormalities of auditory processing in ASD ('electrophysiological signatures') and their clinical correlates. These findings offer promise for the comprehensive assessment of developmental neuropsychiatric disorders.

Indexed as

Evoked Potentials, AuditoryAcoustic StimulationAdolescentAutistic DisorderBrain MappingChildChild, PreschoolElectroencephalographyHumansLanguage Development DisordersMagnetoencephalographyReaction Time

Identifiers

PMID18336941
PMCPMC2397446
OpenAlexW2002753757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.