ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2006
Increased intra-abdominal pressure: is it of any consequence in severe acute pancreatitis?
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intra-abdominal Hypertension Is a Strong Predictor of Mortality and Poor Clinical Outcome in Severe Acute Pancreatitis.Digestive diseases and sciences · 2025Pooled it
- Intra-abdominal pressure: Time ripe to revise management guidelines of acute pancreatitis?World journal of gastrointestinal pathophysiology · 2016Article
- Article
- Intra-abdominal pressure in the early phase of severe acute pancreatitis: canary in a coal mine? Results from a rigorous validation protocol.Gut and liver · 2013Article
- Focused open necrosectomy in necrotizing pancreatitis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2013Article
- Risk factors and outcome of intra-abdominal hypertension in patients with severe acute pancreatitis.World journal of surgery · 2012Article
- Intra-abdominal pressure and abdominal perfusion pressure: which is a better marker of severity in patients with severe acute pancreatitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2011Article
- Conservative approach in the management of severe acute pancreatitis: eight-year experience in a single institution.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2008Article
- Continuous veno-venous haemofiltration in the treatment of severe acute pancreatitis: 6-year experience.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2007Article
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Authors and funding
4 authors.
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Abstract
backgroundIncreased intra-abdominal pressure (IAP) is detrimental for the recovery of organ function in trauma and emergency patients. The aim of this study was to assess the correlation between the dynamics of IAP and organ dysfunction in severe acute pancreatitis (SAP). MATERIALS AND
methodsManagement of SAP between 2000 and 2004 was analysed. SAP was classified according to Atlanta 1992. Organ dysfunction, systemic inflammatory response syndrome (SIRS) and outcomes in relation to the IAP were assessed. IAP was measured indirectly.
resultsA total of 65 patients, with an average APACHE II score of 6.44, complied with the Atlanta criteria. In all, 34 patients received conservative treatment and 31 were operated. SIRS was observed in 59 cases and multiple organ dysfunction syndrome (MODS) in 61 cases. IAP was significantly higher in the 25 most complicated patients requiring renal replacement therapy (RRT), compared with 40 patients without RRT, 31.72 vs 21.4 cm/H(2)O (p=0.037). IAP interrelated positively with SOFA score (r = + 0.371, p<0.01) and organs involved (r = + 0.356, p<0.01), and negatively with platelet count and enterally provided volume (r = - 0.284, p<0.01; r = - 0.5, p<0.01, respectively). Overall mortality (9.2%) was associated with surgery and sustained increase of the IAP over 25 cm/H(2)O. Our data support the pathophysiological interrelation of elevated IAP and development of organ dysfunction.
conclusionDevelopment of organ dysfunction in SAP could be associated with increased IAP. Grade III increase of IAP should be considered as an indicator for revision of treatment modalities.
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