Evidence map›Paper›PMID 18330727›Full record

ReviewClinical reviews in allergy & immunology2008

Host factors in amniotic fluid and breast milk that contribute to gut maturation.

Carol L Wagner, Sarah N Taylor, Donna Johnson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical reviews in allergy & immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
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  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. The Microbiota-Gut-Brain Axis and Epilepsy.Cellular and molecular neurobiology · 2022
    Review
  14. Review
  15. Nutritional and Functional Properties of Colostrum in Puppies and Kittens.Animals : an open access journal from MDPI · 2021
    Review
  16. Article
  17. Article
  18. The Role of the Microbiota in Regeneration-Associated Processes.Frontiers in cell and developmental biology · 2021
    Review
  19. Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carol L WagnerDivision of Neonatology, Department of Pediatrics, Medical University of South Carolina, 173 Ashley Avenue, P.O. Box 250513, Charleston, SC 29425, USA. wagnercl@musc.edu
Sarah N Taylor
Donna Johnson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut represents a complex organ system with regional differences, which reflect selective digestive and absorptive functions that change constantly in response to bodily requirements and the outside milieu. As a barrier to the external environment, gut epithelium must be renewed rapidly and repeatedly. Growth and renewal of gut epithelial cells is dependent on controlled cell stimulation and proliferation by a number of signaling processes and agents, including gut peptides-both endogenous and exogenous sources. This cascade of events begins during fetal development; with the ingestion of amniotic fluid, this process is enhanced and continued during infancy and early childhood through the ingestion of human milk. Events influenced by amniotic fluid during fetal development and those influenced by human milk that unfold after birth and early childhood to render the gut mature are presented.

Indexed as

Amniotic FluidEpithelial CellsFetal DevelopmentGastrointestinal TractHumansInfant, NewbornInfant Nutritional Physiological PhenomenaIntercellular Signaling Peptides and ProteinsMilk, HumanPermeabilityIntercellular Signaling Peptides and Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.