Evidence map›Paper›PMID 18329302›Full record

ReviewVeterinary journal (London, England : 1997)2008

Uterine diseases in cattle after parturition.

I Martin Sheldon, Erin J Williams, Aleisha N A Miller, Deborah M Nash, Shan Herath

Open access · hybridAbstract readReview
In one paragraph

Review in Veterinary journal (London, England : 1997), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 462 citations in OpenAlex.

  1. Trial
  2. The Puerperium in the Modern Dairy Cow: A Review.Reproduction in domestic animals = Zuchthygiene · 2026
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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

I Martin SheldonDepartment of Veterinary Clinical Sciences, Royal Veterinary College, Royal College Street, London NW1 0TU, UK. sheldon@rvc.ac.uk
Erin J Williams
Aleisha N A Miller
Deborah M Nash
Shan Herath
Royal Veterinary College · GB

Funding

Biotechnology and Biological Sciences Research Council BB/D02028X/1Biotechnology and Biological Sciences Research Council BB/E527155/1Biotechnology and Biological Sciences Research Council BB/F005121/1Biotechnology and Biological Sciences Research Council S19795Wellcome Trust 064155
6 · The paper itself

Abstract

Bacterial contamination of the uterine lumen is common in cattle after parturition, often leading to infection and uterine disease. Clinical disease can be diagnosed and scored by examination of the vaginal mucus, which reflects the presence of pathogenic bacteria such as Escherichia coli and Arcanobacterium pyogenes. Viruses may also cause uterine disease and bovine herpesvirus 4 (BoHV-4) is tropic for endometrial cells, causing a rapid cytopathic effect. The elimination of pathogens by the innate immune system is dependent on pattern recognition receptors binding pathogen-associated molecules. Uterine epithelial and stromal cells express receptors such as Toll-like Receptor 4 that binds E. coli lipopolysaccharide. The infertility associated with uterine disease is caused by damage to the endometrium and disruption of ovarian cyclic activity. Bacteria modulate endometrial prostaglandin secretion, and perturb ovarian follicle growth and function. Understanding the molecular basis of uterine disease will lead to novel approaches to treating infertility.

Indexed as

AnimalsCattleCattle DiseasesFemaleInfertilityPostpartum PeriodPuerperal InfectionUterine DiseasesVagina

Identifiers

PMID18329302
PMCPMC2706386
OpenAlexW2078361108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.