ReviewLancet (London, England)2008
Liver cirrhosis.
Review in Lancet (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 941 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase 1/2 Study of UC-MSC Treatment for the Evaluation the Efficacy and Safety in Patients With Liver Cirrhosis
Using MRI for a Non-invasive Evaluation of Portal Pressure
Promotoras de Donación: Leveraging Community Health Workers to Increase Donor Registration of Older Hispanics
Who cites it
941 citing papers in PubMed, 11 syntheses or guidelines pooled it, 1,861 citations in OpenAlex.
- Association between periodontitis and non-alcoholic fatty liver disease in community-dwelling adults: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Comparing nurse-assisted outpatient follow-up with standard care among patients with decompensated liver cirrhosis: a systematic review and meta-analysis.European journal of gastroenterology & hepatology · 2026Pooled it
- Magnetic resonance T1ρ relaxation in patients with liver fibrosis: a systematic review and meta-analysis.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Pooled it
- From fibrosis regression to recompensation: bibliometric and clinical evidence mapping of disease modification in cirrhosis.Frontiers in medicine · 2026Pooled it
- Management of acute variceal bleeding: updated APASL guidelines.Hepatology international · 2025Guideline
- Prevalent osteoporosis and fracture risk in patients with hepatic cirrhosis: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- EFFECT OF PHYSICAL EXERCISE ON THE HEALTH-RELATED QUALITY OF LIFE ASSESSED BY CLDQ OF LIVER CIRRHOSIS PATIENTS: SYSTEMATIC REVIEW WITH META-ANALYSIS.Arquivos de gastroenterologia · 2025Pooled it
- Adiponectin as a biomarker in liver cirrhosis-A systematic review and meta-analysis.European journal of clinical investigation · 2025Pooled it
- Non-invasive methods for diagnosing portal hypertension and variceal bleeding due to liver cirrhosis secondary to NAFLD/MASLD: systematic review.Frontiers in medicine · 2024Pooled it
- Role of granulocyte colony stimulating factor in the treatment of cirrhosis of liver: a systematic review.The Journal of international medical research · 2023Pooled it
- Dose Recommendations for Common Drugs in Patients with Liver Cirrhosis: A Systematic Literature Review.Clinical drug investigation · 2023Pooled it
- Insulin Resistance and Hepatocellular Carcinoma Development in Chronic Hepatitis B Patients Under Antiviral Therapy.Journal of Korean medical science · 2026Observational
- Hepatic sarcoidosis presenting with portal hypertension without histologically established cirrhosis and reticular hepatic imaging features.Clinical journal of gastroenterology · 2026Article
- Systemic Therapy for Advanced Hepatocellular Carcinoma with Impaired Liver Function: Navigating the Evidence Gap.Cancers · 2026Review
- Article
- Hepatic stellate cells in alcoholic liver cirrhosis: mechanisms of fibrogenesis, plasticity, and fibrosis reversal.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Review
- Bioimpedance Analysis to Predict Clinical Outcomes of Liver Cirrhosis in a Prospective Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Age-Stratified Mortality Outcomes Associated with Nonselective Beta-Blocker Use in Patients with Decompensated Cirrhosis.Journal of clinical medicine · 2026Article
- Application of the Child-Pugh Classification in Japanese Drug Labeling: A Cross-Sectional Analysis of Contraindications, Dose Recommendations, and Pharmacokinetic Rationale.Therapeutic innovation & regulatory science · 2026Article
- Liver Stiffness Variability and Limited Performance of Non-Invasive Fibrosis Scores in Hemodialysis: A Prospective Study.Diagnostics (Basel, Switzerland) · 2026Article
881 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury, which leads to portal hypertension and end-stage liver disease. Recent advances in the understanding of the natural history and pathophysiology of cirrhosis, and in treatment of its complications, have resulted in improved management, quality of life, and life expectancy of patients. Liver transplantation remains the only curative option for a selected group of patients, but pharmacological treatments that can halt progression to decompensated cirrhosis or even reverse cirrhosis are currently being developed. This Seminar focuses on the diagnosis, complications, and management of cirrhosis, and new clinical and scientific developments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.