Evidence map›Paper›PMID 18328709›Full record

ReviewTrends in cell biology2008

Regulation of actin cytoskeleton dynamics by Arf-family GTPases.

Kenneth R Myers, James E Casanova

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed.

  1. Article
  2. Article
  3. Arf1 and ARFGEF2/Sec71 control neuroblast polarity by anchoring nonmuscle myosin II.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Loss of ARF5 impairs recovery after lysosomal damage.Frontiers in molecular biosciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Frontiers in cell and developmental biology · 2021
    Review
  16. Article
  17. TheMolecular biology of the cell · 2020
    Article
  18. Article
  19. Article
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kenneth R MyersDepartment of Cell Biology, University of Virginia Health System, Charlottesville, VA 22908-0732, USA.
James E Casanova

Funding

TRAINING IN CELL AND MOLECULAR BIOLOGYT32GM008136 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI STUKENBERG, P. TODD · 1985 to 2020
$8.5M
The Role of Arf GTPases in Endocytosis and Postendocytic TransportR01GM078585 · NIGMS · UNIVERSITY OF VIRGINIA · PI CASANOVA, JAMES E. · 2007 to 2010
$1.3M
NIGMS NIH HHS R01 GM078585NIGMS NIH HHS T32 GM008136
6 · The paper itself

Abstract

Small GTPases of the Arf family are best known for their role in vesicular transport, wherein they nucleate the assembly of coat proteins at sites of carrier vesicle formation. However, accumulating evidence indicates that the Arfs are also important regulators of actin cytoskeleton dynamics and are involved in a variety of actin-based processes, including cell adhesion, migration and neurite outgrowth. The mechanisms of this regulation are remarkably diverse, ranging from the integration of vesicular transport with cytoskeleton assembly to the direct regulation of Rho-family GTPase function. Here, we review recent progress in our understanding of how Arfs and their interacting proteins function to integrate membrane and cytoskeletal dynamics.

Indexed as

Gene Expression Regulation, EnzymologicActinsADP-Ribosylation Factor 1AnimalsBiological TransportCytoskeletonGolgi ApparatusGTP PhosphohydrolasesHumansModels, BiologicalPhosphatidylinositolsProtein Transportrac GTP-Binding Proteinsrho GTP-Binding ProteinsActinsADP-Ribosylation Factor 1GTP PhosphohydrolasesPhosphatidylinositolsrac GTP-Binding Proteinsrho GTP-Binding Proteins

Identifiers

PMID18328709
PMCPMC2885709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.