ArticleSkeletal radiology2008
Laws' masks descriptors applied to bone texture analysis: an innovative and discriminant tool in osteoporosis.
Article in Skeletal radiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Artificial intelligence on opportunistic computed tomography for predicting vertebral fracture risk in women undergoing estrogen deprivation therapy for breast cancer.La Radiologia medica · 2026Article
- U-Net-Based Deep Learning Hybrid Model: Research and Evaluation for Precise Prediction of Spinal Bone Density on Abdominal Radiographs.Bioengineering (Basel, Switzerland) · 2025Article
- Development of a classification method for mild liver fibrosis using non-contrast CT image.International journal of computer assisted radiology and surgery · 2022Article
- Artificial intelligence-based radiomics on computed tomography of lumbar spine in subjects with fragility vertebral fractures.Journal of endocrinological investigation · 2022Article
- Use of machine learning to select texture features in investigating the effects of axial loading on TEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022Article
- Vertebral body insufficiency fractures: detection of vertebrae at risk on standard CT images using texture analysis and machine learning.European radiology · 2019Article
- Texture analysis of paraspinal musculature in MRI of the lumbar spine: analysis of the lumbar stenosis outcome study (LSOS) data.Skeletal radiology · 2018Article
- Can Laws Be a Potential PET Image Texture Analysis Approach for Evaluation of Tumor Heterogeneity and Histopathological Characteristics in NSCLC?Journal of digital imaging · 2018Article
- 3D bone texture analysis as a potential predictor of radiation-induced insufficiency fractures.Quantitative imaging in medicine and surgery · 2018Article
- Normative values for CT-based texture analysis of vertebral bodies in dual X-ray absorptiometry-confirmed, normally mineralized subjects.Skeletal radiology · 2017Article
- Bone texture analysis using CT-simulation scans to individuate risk parameters for radiation-induced insufficiency fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Semiautomatic tumor segmentation with multimodal images in a conditional random field framework.Journal of medical imaging (Bellingham, Wash.) · 2016Article
- Decreased Bone Formation Explains Osteoporosis in a Genetic Mouse Model of Hemochromatosiss.PloS one · 2016Article
- Characterization of primary and secondary malignant liver lesions from B-mode ultrasound.Journal of digital imaging · 2013Article
- New imaging modalities in bone.Current rheumatology reports · 2011Review
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6 authors.
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Abstract
objectiveThe objective of this study was to explore Laws' masks analysis to describe structural variations of trabecular bone due to osteoporosis on high-resolution digital radiographs and to check its dependence on the spatial resolution. Laws' masks are well established as one of the best methods for texture analysis in image processing and are used in various applications, but not in bone tissue characterisation. This method is based on masks that aim to filter the images. From each mask, five classical statistical parameters can be calculated. MATERIALS AND
methodsThe study was performed on 182 healthy postmenopausal women with no fractures and 114 age-matched women with fractures [26 hip fractures (HFs), 29 vertebrae fractures (VFs), 29 wrist fractures (WFs) and 30 other fractures (OFs)]. For all subjects radiographs were obtained of the calcaneus with a new high-resolution X-ray device with direct digitisation (BMA, D3A, France). The lumbar spine, femoral neck, and total hip bone mineral density (BMD) were assessed by dual-energy X-ray absorptiometry.
resultsIn terms of reproducibility, the best results were obtained with the TRE5E5 mask, especially for three parameters: "mean", "standard deviation" and "entropy" with, respectively, in vivo mid-term root mean square average coefficient of variation (RMSCV)%= 1.79, 4.24 and 2.05. The "mean" and "entropy" parameters had a better reproducibility but "standard deviation" showed a better discriminant power. Thus, for univariate analysis, the difference between subjects with fractures and controls was significant (P<10(-3)) and significant for each fracture group independently (P<10(-4) for HF, P=0.025 for VF and P< 10(-3) for OF). After multivariate analysis with adjustment for age and total hip BMD, the difference concerning the "standard deviation" parameter remained statistically significant between the control group and the HF and VF groups (P<5 x 10(-5), and P=0.04, respectively). No significant correlation between these Laws' masks parameters and BMD was obtained. In addition, this study showed the dependence of Laws' masks parameters on image resolution, which confirms the necessity to perform Laws' textural measurement on high-resolution images.
conclusionThe reproducibility and discriminant power of the Laws' masks analysis has been demonstrated on bone images; thus, this method constitutes a promising routine technique for the determination of osteoporosis fracture risk from radiographs.
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