ArticleJournal of clinical hypertension (Greenwich, Conn.)2008
Mechanisms and treatment of resistant hypertension.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- The Global Burden of Resistant Hypertension and Potential Treatment Options.European cardiology · 2024Review
- The Effect of Non-Surgical Periodontal Treatment on Patients with Combined Refractory Arterial Hypertension and Stage III, Grade B Periodontitis: A Preliminary Prospective Clinical Study.Journal of clinical medicine · 2023Article
- When blood pressure refuses to budge: exploring the complexity of resistant hypertension.Frontiers in cardiovascular medicine · 2023Review
- Article
- Gut-Brain Axis in Regulation of Blood Pressure.Frontiers in physiology · 2017Review
- Drug Development for Hypertension: Do We Need Another Antihypertensive Agent for Resistant Hypertension?Current hypertension reports · 2016Review
- Do Obese Individuals With Hypertension Have More Difficult-to-Control Blood Pressure and End Organ Damage Than Their Nonobese Counterparts?Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- The effect of plasmapheresis on blood pressure in voluntary plasma donors.Vox sanguinis · 2015Article
- Prescribing patterns in the treatment of hypertension among underserved African American elderly.Ethnicity & disease · 2014Article
- Resistant hypertension--its identification and epidemiology.Nature reviews. Nephrology · 2013Review
- Genetic and Adverse Health Outcome Associations with Treatment Resistant Hypertension in GenHAT.International journal of hypertension · 2013Article
- Management of hypertension in the elderly.Nature reviews. Cardiology · 2012Review
- Epidemiology of resistant hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2011Review
- Cardiovascular Regulation in Obstructive Sleep Apnea.Drug discovery today. Disease models · 2011Article
- Resistant hypertension workup and approach to treatment.International journal of hypertension · 2010Article
- Hypertension: issues in control and resistance.Current hypertension reports · 2009Review
- Aldosterone excess or escape: Treating resistant hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2009Article
- Clinical approach in treatment of resistant hypertension.Integrated blood pressure control · 2009Article
- Prevalence and characteristics of resistant hypertensive patients in an Asian population.Indian heart journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resistant hypertension is defined as blood pressure (BP) that remains uncontrolled in spite of the use of >/=3 antihypertensive medications. Stricter BP goals, higher obesity rates, older age, and increased use of exogenous BP-elevating substances are related to an increasing prevalence of resistant hypertension. The evaluation of patients with resistant hypertension is focused on identifying contributing and secondary causes of hypertension, including hyperaldosteronism, obstructive sleep apnea, chronic kidney disease, renal artery stenosis, and pheochromocytoma. Hyperaldosteronism is now recognized as the most common cause of resistant hypertension, and all patients with resistant hypertension should be screened with a plasma aldosterone/renin ratio even if the serum potassium level is normal. Treatment includes removal of contributing factors, appropriate management of secondary causes, and use of effective multidrug regimens. Recent studies indicate that the addition of spironolactone to standard treatment induces significant BP reduction in most patients with resistant hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.