ArticleThe Plant cell2008
Modulation of nitrosative stress by S-nitrosoglutathione reductase is critical for thermotolerance and plant growth in Arabidopsis.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers.
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Who cites it
130 citing papers in PubMed, 364 citations in OpenAlex.
- Modulation of GSNOR activity for improved NO homeostasis and flood resilience in plants.Plant signaling & behavior · 2026Review
- A key role for S-nitrosylation in immune regulation and development in the liverwort Marchantia polymorpha.Journal of experimental botany · 2026Article
- Aboveground whole-plant live HRedox biology · 2026Article
- GSNOR mediates NO signaling to enhance salt tolerance in tobacco by regulating redox and photosynthesis.Photosynthesis research · 2026Article
- Nitrate Reductase GenesBiomolecules · 2026Article
- GSNOR is essential for nitric oxide homeostasis and involved in aflatoxin biosynthesis and pathogenicity inApplied and environmental microbiology · 2026Article
- The Central Role of GSNOR: Decoding Nitric Oxide Signaling for Crop Stress Tolerance.International journal of molecular sciences · 2025Review
- Functional interactions among H2O2, NO, H2S, and melatonin in the physiology, metabolism, and quality of horticultural Solanaceae.Journal of experimental botany · 2025Review
- Exploring the regulatory roles of AtGLR3.4 receptors in mitochondrial stress and ROS management in Arabidopsis.Plant cell reports · 2025Article
- Melatonin a day: Mitigates saline-alkali stress away!The Plant cell · 2025Article
- Melatonin confers saline-alkali tolerance in tomato by alleviating nitrosative damage and S-nitrosylation of H+-ATPase 2.The Plant cell · 2025Article
- Hot to Go: The impact of protein nitrosylation on plant fertility.Plant physiology · 2025Article
- Nitro-fatty acids modulate germination onset through S-nitrosothiol metabolism.Plant physiology · 2025Article
- ANAC044 orchestrates mitochondrial stress signaling to trigger iron-induced stem cell death in root meristems.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Computational exploration ofJournal of biosciences · 2025Article
- Nitric oxide-mediated thermomemory: a new perspective on plant heat stress resilience.Frontiers in plant science · 2025Review
- Nitric oxide in plants: an insight on redox activity and responses toward abiotic stress signaling.Plant signaling & behavior · 2024Review
- Maternal nitric oxide homeostasis impacts female gametophyte development under optimal and stress conditions.The Plant cell · 2024Article
- Genome-Wide Identification of PYL/RCAR ABA Receptors and Functional Analysis ofPlants (Basel, Switzerland) · 2024Article
- Supersulfide catalysis for nitric oxide and aldehyde metabolism.Science advances · 2023Article
70 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Nitric oxide (NO) is a key signaling molecule in plants. This analysis of Arabidopsis thaliana HOT5 (sensitive to hot temperatures), which is required for thermotolerance, uncovers a role of NO in thermotolerance and plant development. HOT5 encodes S-nitrosoglutathione reductase (GSNOR), which metabolizes the NO adduct S-nitrosoglutathione. Two hot5 missense alleles and two T-DNA insertion, protein null alleles were characterized. The missense alleles cannot acclimate to heat as dark-grown seedlings but grow normally and can heat-acclimate in the light. The null alleles cannot heat-acclimate as light-grown plants and have other phenotypes, including failure to grow on nutrient plates, increased reproductive shoots, and reduced fertility. The fertility defect of hot5 is due to both reduced stamen elongation and male and female fertilization defects. The hot5 null alleles show increased nitrate and nitroso species levels, and the heat sensitivity of both missense and null alleles is associated with increased NO species. Heat sensitivity is enhanced in wild-type and mutant plants by NO donors, and the heat sensitivity of hot5 mutants can be rescued by an NO scavenger. An NO-overproducing mutant is also defective in thermotolerance. Together, our results expand the importance of GSNOR-regulated NO homeostasis to abiotic stress and plant development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.